Tumor Syndromes Flashcards

1
Q

Tuberous Sclerosis

A
AD
Facial lesions (adenoma sebaceum), ash-leaf spots, cortical and retinal hamartomas, seizures, mental retardation, renal cysts, cardiac rhabdomyomas, increased incidence of astrocytomas, mitral regurgitation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Osler-Weber-Rendu Syndrome

A

AD

Inherited disorder of blood vessels - telangiectasia, recurrent epistaxis, skin discoloration, AV malformations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Neurofibromatosis Type I (von Recklinghausen’s Disease)

A

AD
Chromosome 17
Cafe-au-lait spots, neural tumors, Lisch nodules, scoliosis, optic pathway gliomas, pheochromocytomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Neurofibromatosis Type II

A

AD
Chromosome 22
Bilateral acoustic schwannomas, juvenile cataracts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

von Hippel Lindau Disease

A

AD
Chromosome 3
Hemangioblastomas of retina/cerebellum/medulla, bilateral renal cell carcinoma, pheochromocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

WAGR Complex

A

Wilms’ tumor (nephroblastoma), Aniridia, Genitourinary malformation, mental Retardation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Beckwith-Wiedemann Syndrome

A

Wilms’ tumor, neonatal hypoglycemia, muscular hemihypertrophy, organomegaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Sturge-Weber Syndrome

A

Congential disorder - port-wine stains, ipsilateral leptomeningeal angioma, pheochromocytoma, glaucoma, seizure, hemiparesis, mental retardation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

MEN type 1

A
Parathyroid tumor (hypercalcemia)
Pancreatic tumor (gastrin)
Pituitary adenoma (prolactin, ACTH)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

MEN type 2A

A

Medullary carcinoma of the thyroid (calcitonin)
Pheochromocytoma
Parathyroid tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

MEN type 2B

A

Medullary carcinoma of the thyroid (calcitonin)
Pheochromocytoma
Marfanoid habitus/Mucosal neuromas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly