Pysch Drugs

Question 1

Preferred drug(s) for alcohol withdrawal

Answer 1

Benzodiazepines

Question 2

Preferred drug(s) for anxiety

Answer 2

SSRIs, SNRIs, buspirone

Question 3

Preferred drug(s) for ADHD

Answer 3

Methylphenidate, amphetamines

Question 4

Preferred drug(s) for bipolar disorder

Answer 4

“Mood stabilizers” (e.g. lithium, valproic acid, carbamazepine), atypical antipsychotics

Question 5

Preferred drug(s) for bulimia

Answer 5

SSRIs

Question 6

Preferred drug(s) for depression

Answer 6

SSRIs, SNRIs, TCAs, buspirone, mirtazapine (especially with insomnia)

Question 7

Preferred drug(s) for OCD

Answer 7

SSRIs, clomipramine

Question 8

Preferred drug(s) for panic disorder

Answer 8

SSRIs, venlaxafine, benzodiazepines

Question 9

Preferred drug(s) for PTSD

Answer 9

SSRIs

Question 10

Preferred drug(s) for schizophrenia

Answer 10

Antipscyhotics

Question 11

Preferred drug(s) for social phobias

Answer 11

SSRIs

Question 12

Preferred drug(s) for Tourette’s

Answer 12

Antipsychotics (e.g. haloperidol, risperidone)

Question 13

Drugs classified as typical antipsychotics

Answer 13

Haloperidol and the “-azines”

Question 14

MOA of typical antipsychotics

Answer 14

Block dopamine D2 receptors (increases cAMP)

Question 15

SE of typical antipsychotics

Answer 15

EPS side effects (dyskinesias), endocrine side effects (galactorrhea)

Side effects arising from blocking muscarinic (dry mouth, constipation), alpha-1 (hypotension), and histamine (sedation) receptors

Question 16

Symptoms of neuroleptic malignant syndrome caused by typical antipsychotics

Answer 16

Think FEVER

Fever
Encephalopathy
Vitals unstable
Elevated enzymes
Rigidity of muscles

Question 17

Treatment of neuroleptic malignant syndrome

Answer 17

Dantrolene, D2 agonists (bromocriptine)

Question 18

Symptoms of tardive dyskinesia caused by typical antipsychotics

Answer 18

Stereotypical facial movements as a result of long-term antipsychotic use, often irreversible

Question 19

Typical antipsychotic that can cause corneal deposits

Answer 19

Chlorpromazine

Question 20

Typical antipsychotic that can cause retinal deposits

Answer 20

Thioridazine

Question 21

Drugs classified as atypical antipsychotics

Answer 21

Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone

Question 22

MOA of atypical antipsychotics

Answer 22

Varied effects on 5-HT2, dopamine, and alpha and H1 receptors

Question 23

Atypical antipsychotic associated with agranulocytosis and seizures

Answer 23

Clozapine

Question 24

Atypical antipsychotic associated with prolonged QT interval

Answer 24

Ziprasidone

Question 25

MOA of buspirone

Answer 25

Stimulates 5-HT1A receptors, takes 1-2 weeks to take effect

Question 26

Indication of buspirone

Answer 26

Generalized anxiety disorder

Question 27

Drugs classified as SSRIs

Answer 27

Fluoxetine, paroxetine, sertraline, citalopram

Question 28

SE of SSRIs

Answer 28

GI distress, sexual dysfunction (anorgasmia and decreased libido) Serotonin syndrome: with any drug that increases serotonin resulting in hyperthermia, confusion, myoclonus, cardiovascular collapse, flushing, diarrhea, seizures

Question 29

Treatment of serotonin syndrome

Answer 29

Cyproheptadine (5-HT2 receptor antagonist)

Question 30

Drugs classified as SNRIs

Answer 30

Venlafaxine, duloxetine

Question 31

SNRI that can be used to treat diabetic peripheral neuropathy

Answer 31

Duloxetine

Question 32

SE of SNRIs

Answer 32

Increased BP, sedation, nausea, risk of inducing mania

Question 33

Drugs classified as TCAs

Answer 33

Amitryptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin, amoxapine

Question 34

MOA of TCAs

Answer 34

Block reuptake of NE and serotonin

Question 35

TCA that can be used to treat bedwetting

Answer 35

Imipramine

Question 36

TCA that can be used to treat OCD

Answer 36

Clomipramine

Question 37

SE of TCAs

Answer 37

Postural hypotension, atropine like effects (tachycardia, urinary retention, dry mouth) Tri-C's: Convulsions, Coma, Cardiotoxicity

Question 38

Treatment of TCA cardiovascular toxicity

Answer 38

NaHCO3

Question 39

Drugs classified as MAOIs

Answer 39

Tranycypromine, phenelzine, isocarboxazid, selegiline (selective MAO-B inhibitor)

Question 40

MOA of MAO-Is

Answer 40

Nonselective MAO inhibition increases levels of amine neurotransmitters (NE, serotonin, dopamine)

Question 41

SE of MAO-Is

Answer 41

Hypertensive crisis (most notably with ingestion of tyramine in wines and cheeses), CNS stimulation

Question 42

MOA of mirtazapine

Answer 42

Alpha-2 antagonist (increases release of NE and serotonin) and potent 5-HT2 and 5-HT3 receptor antagonist

Question 43

MOA of maprotiline

Answer 43

Blocks NE reuptake

Question 44

MOA of trazodone

Answer 44

Inhibits serotonin reuptake

Question 45

SE of trazodone

Answer 45

Sedation, nausea, priapism, postural hypotension