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Board Review > Pysch Drugs > Flashcards

Pysch Drugs Flashcards

1
Q

Preferred drug(s) for alcohol withdrawal

A

Benzodiazepines

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2
Q

Preferred drug(s) for anxiety

A

SSRIs, SNRIs, buspirone

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3
Q

Preferred drug(s) for ADHD

A

Methylphenidate, amphetamines

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4
Q

Preferred drug(s) for bipolar disorder

A

“Mood stabilizers” (e.g. lithium, valproic acid, carbamazepine), atypical antipsychotics

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5
Q

Preferred drug(s) for bulimia

A

SSRIs

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6
Q

Preferred drug(s) for depression

A

SSRIs, SNRIs, TCAs, buspirone, mirtazapine (especially with insomnia)

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7
Q

Preferred drug(s) for OCD

A

SSRIs, clomipramine

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8
Q

Preferred drug(s) for panic disorder

A

SSRIs, venlaxafine, benzodiazepines

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9
Q

Preferred drug(s) for PTSD

A

SSRIs

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10
Q

Preferred drug(s) for schizophrenia

A

Antipscyhotics

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11
Q

Preferred drug(s) for social phobias

A

SSRIs

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12
Q

Preferred drug(s) for Tourette’s

A

Antipsychotics (e.g. haloperidol, risperidone)

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13
Q

Drugs classified as typical antipsychotics

A

Haloperidol and the “-azines”

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14
Q

MOA of typical antipsychotics

A

Block dopamine D2 receptors (increases cAMP)

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15
Q

SE of typical antipsychotics

A

EPS side effects (dyskinesias), endocrine side effects (galactorrhea)

Side effects arising from blocking muscarinic (dry mouth, constipation), alpha-1 (hypotension), and histamine (sedation) receptors

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16
Q

Symptoms of neuroleptic malignant syndrome caused by typical antipsychotics

A

Think FEVER

Fever
Encephalopathy
Vitals unstable
Elevated enzymes
Rigidity of muscles
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17
Q

Treatment of neuroleptic malignant syndrome

A

Dantrolene, D2 agonists (bromocriptine)

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18
Q

Symptoms of tardive dyskinesia caused by typical antipsychotics

A

Stereotypical facial movements as a result of long-term antipsychotic use, often irreversible

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19
Q

Typical antipsychotic that can cause corneal deposits

A

Chlorpromazine

20
Q

Typical antipsychotic that can cause retinal deposits

A

Thioridazine

21
Q

Drugs classified as atypical antipsychotics

A

Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone

22
Q

MOA of atypical antipsychotics

A

Varied effects on 5-HT2, dopamine, and alpha and H1 receptors

23
Q

Atypical antipsychotic associated with agranulocytosis and seizures

24
Q

Atypical antipsychotic associated with prolonged QT interval

A

Ziprasidone

25
Q

MOA of buspirone

A

Stimulates 5-HT1A receptors, takes 1-2 weeks to take effect

26
Q

Indication of buspirone

A

Generalized anxiety disorder

27
Q

Drugs classified as SSRIs

A

Fluoxetine, paroxetine, sertraline, citalopram

28
Q

SE of SSRIs

A

GI distress, sexual dysfunction (anorgasmia and decreased libido)

Serotonin syndrome: with any drug that increases serotonin resulting in hyperthermia, confusion, myoclonus, cardiovascular collapse, flushing, diarrhea, seizures

29
Q

Treatment of serotonin syndrome

A

Cyproheptadine (5-HT2 receptor antagonist)

30
Q

Drugs classified as SNRIs

A

Venlafaxine, duloxetine

31
Q

SNRI that can be used to treat diabetic peripheral neuropathy

A

Duloxetine

32
Q

SE of SNRIs

A

Increased BP, sedation, nausea, risk of inducing mania

33
Q

Drugs classified as TCAs

A

Amitryptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin, amoxapine

34
Q

MOA of TCAs

A

Block reuptake of NE and serotonin

35
Q

TCA that can be used to treat bedwetting

A

Imipramine

36
Q

TCA that can be used to treat OCD

A

Clomipramine

37
Q

SE of TCAs

A

Postural hypotension, atropine like effects (tachycardia, urinary retention, dry mouth)

Tri-C’s: Convulsions, Coma, Cardiotoxicity

38
Q

Treatment of TCA cardiovascular toxicity

39
Q

Drugs classified as MAOIs

A

Tranycypromine, phenelzine, isocarboxazid, selegiline (selective MAO-B inhibitor)

40
Q

MOA of MAO-Is

A

Nonselective MAO inhibition increases levels of amine neurotransmitters (NE, serotonin, dopamine)

41
Q

SE of MAO-Is

A

Hypertensive crisis (most notably with ingestion of tyramine in wines and cheeses), CNS stimulation

42
Q

MOA of mirtazapine

A

Alpha-2 antagonist (increases release of NE and serotonin) and potent 5-HT2 and 5-HT3 receptor antagonist

43
Q

MOA of maprotiline

A

Blocks NE reuptake

44
Q

MOA of trazodone

A

Inhibits serotonin reuptake

45
Q

SE of trazodone

A

Sedation, nausea, priapism, postural hypotension

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