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VPH 122 (3rd exam) > Tuberculosis > Flashcards

Tuberculosis Flashcards

1
Q

rank of PH in most tuberculosis cases

A

4th

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2
Q

Why is there an increase of Tuberculosis

A
  1. limited diagnostic capacity
  2. limited treatment
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3
Q

Why did TB rise after COVID pandemic?

A

co-morbidity

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4
Q

Can TB be also found in milk and milk products?

A

YES

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5
Q

Disease associated with TB

A

Diabetes

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6
Q

Why did TB cases decline during pandemic?

A

• underdiagnosed
• poor reporting
• focused on COVID

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7
Q

TB is ___% cause of multidrug resistance (2019)

A

30%

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8
Q

TB for animal - humans

A

Mycobacterium Tuberculosis Complex (MBTC)

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9
Q

2 TB spp for human - animals (zooanthroponoses)

[ ta ]

A

M. tuberculosis
M. africanum

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10
Q

TB spp where cattles are both maintenance & incidental host

A

M. caprae

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11
Q

TB spp for rodents

A

M. microti

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12
Q

TB spp for goats

A

M. bovis

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13
Q

TB spp of sea animals

A

M. pinnipedii

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14
Q

TB spp of large ruminants & NHP

A

M. orygis

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15
Q

TB spp in Asia

A

M. bovis

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16
Q

ID of TB

A

less than 10

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17
Q

Can TB be latent?

A

YES (5-10% of healthy individuals)

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18
Q

zoonotic mycobacteria usually causes ____ disease

A

extrapulmonary (abdominal & CNS)

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19
Q

Risk factor of TB:
• young or old?
• male or female?
• population density?

A

• Young
• Female (milk)
• high population

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20
Q

disease of M. tuberculosis

A

cutaneous tuberculosis

  • tuberculosis chancre
  • tuberculosis verruccose cutie
  • butcher’s wart
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21
Q

can cutaneous tuberculosis ulcer heal?

A

NO (non-healing ulcer)

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22
Q

When do subclinical TB manifest?

A
  • under stress
  • immunocompromised
23
Q

TB is less common in these 3 animals

x CTH x

A

Cats
Dog
Horse

24
Q

uncalcified nodule itsura

25
(2) TB lesion in horses
1. spleen 2. liver
26
is TB in birds encapsulated?
NO
27
TB in this animal is • slow • chronic • debilitating • lymphadenopathy
Cattle
28
TB in this animal are usually asymptomatic but can cause sudden death
Birds
29
TB in this animal affects “abdominal area”
Horse
30
TB in this animal affects “CNS”
Pigs
31
TB in this animal affects “submandibular”
Cats
32
Infects cattle in airborne transmission (tumatayo bigla)
opposum
33
bacterial culture for TB
1. modified Middlebrook 7H10 / 7H11 2. Stonebrink’s / Lowenstein-Jensen egg-based medium
34
IP required for Lowenstein-Jensen
atleast 2 weeks
35
nawawala curved feature pag inoculated from medium
sputum
36
samples for TB
pooled lymph node (head & thorax) 1. milk 2. feces 3. urine
37
stain for direct microscopy for TB
Ziehl-Neelsen stain
38
genes of M. bovis (2)
1. pncA 2. oxyR
39
worldwide spoligotyping for M. bovis
SB 012 0
40
False-Positive for tuberculin skin test
M. avium
41
Tuberculin skin test is for all animals susceptible to TB
NO (cattle only)
42
more convenient test than CIT
Caudal fold test
43
higher sensitivity & specificity than CFT
Cervical INTRAdermal test
44
Caudal fold test is only for this species
M. bovis
45
Substitute test than tuberculin skin test
Gamma-interferin release assay
46
detects interferon-gamma
Primary coating antibody
47
in ELISPOT assay, this forms color changes
precipitated enzyme SUBSTRATE
48
(2) resistant for TB x IR x
Isoniazid Rifampicin
49
M. bovis is innately resistant to
pyrazinamide
50
Min treatment for M. bovis
9 months
51
To prevent TB, cook meat for:
65C ; atleast 30 mins
52
autoclave for TB
121C ; atleast 15 mins
53
strain of vaccine for TB (route?) M. tuberculosis
Bacillus Calmette Guerin strain (IM, deltoid)
54
vaccine route for M. bovis (cattle)
respiratory / SC

VPH 122 (3rd exam) (26 decks)

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