Colibacillosis Flashcards

1
Q

severe form of colibacillosis in humans

A

severe hemorrhagic colitis

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2
Q

Is Colibacillosis asymptomatic for both humans and animals?

A

NO (animals only)

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3
Q

Colibacillosis is related to ____ diarrhea

A

Traveller’s diarrhea

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4
Q

In Davao del Norte, 3 out of 9 water sources tested positive for this group of bacteria

A

coliforms

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5
Q

50 acute diarrhea cases in Visayan region (Southern Leyte) after this typhoon

A

Typhoon Odette

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6
Q

difference of Commensal & Pathogenic E. coli?

A

exotoxins is present in Pathogenic

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7
Q

Intestinal pathogenic E. coli

[ PHITA Da ]

A

entero:
pathogenic
haemorrhagic
invasive
toxigenic
aggregative

Diffusely adherent

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8
Q

Extraintestinal pathogenic

[ USM ]

A

Uropathogenic
Sepsis-associacted
Meningitis-associated

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9
Q

• most zoonotic cases
• shiga-producing toxin

A

Entero: haemorrhagic
O157 : H7

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10
Q

E. coli in SMALL intestine

[ tpa ]

A

toxigenic
pathogenic
aggregative (+ large intestine)

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11
Q

E. coli in COLON

[ ih ]

A

invasive
haemorrhagic

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12
Q

heat stable & labile enterotoxin

A

ETEC
toxigenic

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13
Q

cytotoxic enterotoxin

A

EIEC
invasive

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14
Q

(2) attaching-effacing lesions

[ ph ]

A

EPEC & EHEC
pathogenic & haemorrhagic

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15
Q

destroys microvilli

A

EPEC
pathogenic

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16
Q

stacked brick appearance

A

EAEC
aggregative

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17
Q

undefined virulencr factor

A

DAEC
diffusely adherent

18
Q

Can Colibacillosis be killed with low/acidic pH?

A

NO
(it survives gastric acidity)

19
Q

How long does Colibacillosis shed in humans?

A

7 - 9 days or longer

20
Q

main transmission of Colibacillosis

21
Q

Colibacillosis is transmitted primarily from what animal meat?

A

Poultry meat

22
Q

Colibacillosis disease in man starts with colonization of ______

A

small & large intestine

23
Q

(2) disease of Colibacillosis in HUMANS

A
  1. Hemorrhagic Colitis
  2. Hemolytic Uremic Syndrome
24
Q

the disease in man with
• prodromal diarrhea
• acute kidney injury
• thrombonic thrombocytopenic purpura (elders)
- brain
- kidney

25
swelling of blood vessels
hemor purpura
26
is there CNS signs (man) in Colibacillosis?
YES
27
(4) Animals affected with Colibacillosis?
1. YOUNG ruminants 2. Dogs 3. Poultry (all ages) 4. Birds
28
Can coligranuloma of poultry be found in spleen?
NO - liver - cecum - duodenum - mesenterium
29
Tranmission of Colibacillosis comes from meat of these 4 animals
1. pigs 2. horses 3. fish 4. POULTRY others - dairy
30
What is the bacterial culture for Colibacillosis?
1) Trypticase soy broth 2) Sorbitol-MacConkey agar + Phage typing
31
most reliable molecular finger-printing technique
Pulsed field gel electrophoresis
32
Detects O & H antigens of Colibacillosis
Immunological & Nucleic acid-based rapid test
33
Treatment to “avoid” HUS & TTP?
Fluid & Electrolyte replacement
34
Can anti-motility drugs be recommended for Colibacillosis?
NO (contraindicated)
35
Antimicrobial choice for Colibacillosis [ EC NGT ] eacy not gonna tell
Enrofloxacin Cephalosporin Neomycin Gentamicin TMPS
36
Resistance for Colibacillosis [ TSS ] taylor swift swift
Tetracycline Streptomycin Sulfa drugs
37
Treatment for humans “with” HUS / TTP (3)
1. Dialysis 2. Blood transfusion 3. Plasmapheresis
38
Animal with vaccine for Colibacillosis
Cattle
39
Vaccine for cattle w/ Colibacillosis is against? give: dose - route - interval-
EHEC O157 : H7 2 dose IM route 3 weeks apart
40
Dose & weeks ap
41
Can Colibacillosis be autoclaved?
YES