Botulism Flashcards

1
Q

Botulism spp that is F toxin

A

C. baratii

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2
Q

Botulism spp that is E toxin

A

C. butyricum

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3
Q

former group IV of C. botulinum

A

C. argentinenee

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4
Q

Botulism toxins of HUMANS

A

A, B, E

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5
Q

Botulism toxins of HORSES

A

toxin B

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6
Q

Botulism toxins of animals

A

C, D, mosaics

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7
Q

pH for Botulism to grow

A

more than pH 4.6

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8
Q

for group 3, type C botulism
pH required?

A

more than 5.1 — 5.4

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9
Q

salt conc needed to grow botulism

A

LESS than 10%

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10
Q

Nitrate level to inhibit Botulism in Philippines

A

100 - 200 ppm

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11
Q

Inactivates toxins of botulism (2)

A
  1. sunlight (1-3 hrs)
  2. 0.1% sodium hypochlorite (1% for vegetative cell)
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12
Q

Botulism in northern regions

A

Type E

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13
Q

most common cause of botulism

A

Infant botulism

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14
Q

spores ID for Botulism

A

10-100 spores/kg

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15
Q

paralysis of C. botulism

A

flaccid paralysis

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16
Q

paralysis of C. tetani

A

spastic paralysis

17
Q

no acetylcholine =

A

no heart contraction

18
Q

Botulism can be fatal in 1 day

19
Q

drug abusers
cosmetic procedure
black tar heroin (SC)

A

wound botulism

20
Q

Age affected with infant botulism (give shedding)

A

LESS than 1 y.o.
(7 months shedding)

21
Q

Floppy baby syndrome

A

Infant botulism

22
Q

Inhalation of accidental injection of toxin

A

Iatrogenic (drug-induced)

23
Q

has higher infectious dose than Foodborne

A

Inhalation botulism

24
Q

Important for ruminants to avoid botulism

A

Phosphorus

25
Young or Old horse?
YOUNG Shaker Foal syndrome (foal) Equine Grass sickness (young adult)
26
botulism for birds
Limberneck
27
diagnosis for Botulism
mouse neutralization test
28
need prior to blood/egg yolk agar culture (2)
1. heat 2. ethanol treatment
29
to stop neuromuscular blockage
Guanidine hydro-chloride
30
Avoid this drug for Botulism
AMINO-glycosides
31
Botulism for wound debridement & antibiotic therapy
penicillin G or metronidazole
32
Why hydrogen peroxide for wound botulism?
it is anaerobic