Brucellosis Flashcards
can Brucellosis survive an acidic environment
NO (dies at pH 3.5)
Brucellosis survives cold environment
TRUE (preferred)
most widespread Brucellosis
B. abortus
Brucellosis spp that is NOT zoonotic
B. ovis (sheep)
which environments (2) do Brucella prefers
1) terrestrial
2) marine
Brucellosis where diff organs are affected
- bone & joints
- CNS
- eyes
- cardiovascular
- respiratory
- reproductive
chronic brucellosis
can Brucella cause abortion in humans as well?
YES
how many times can Brucella cause abortion in:
ruminants =
dogs =
ruminants = once (infertile na)
dogs = recurring
Brucella causes these 2 disease in HORSES
- Fistulous withers
- Poll evil
does Brucella cause death?
RARE
except in fetus
what organ can Brucella persist for longer period of time?
lymph nodes
is the animal infected with Brucella condemned/slaughtered agad?
YES
risk factor for Brucella?
young or old?
male or female?
hot or cold?
agroecology?
old
female
cold
dry climate
is Brucella a neglected zoonoses?
YES
Brucella is risk group?
3 (BSL 3)
gold standard for Brucellosis?
bacterial culture
Brucella spp with rough LPS
[ ams ]
B.
abortus
melitensis
suis
Brucella spp with smooth LPS
[ oc ]
B.
ovis
canis
Serologic tests like:
1) Brucellin skin test
2) Rose Bengal tes
should be tested how many times?
2x
relies on “cell-mediated” immunity for antibody production
Brucellosis
tests for Brucellosis that uses methylene blue (+ is uniform blue solution)
Milk Ring test
treatment of Brucella for more than 8 y/o & adults?
doxycycline (PO)
gentamicin (IM)
treatment of Brucella for less than 8 y/o ?
trimethoprim sulfamethoxazole (PO)
gentamicin (IV / IM)
treatment of Brucella for pregant humans?
trimethoprim sulfamethoxazole (PO)
rifampicin (PO)
treatment of Brucella for animals?
long term antibiotics with
• doxycycline
• gentamicin
Brucella may cross react with
[ FEYV ]
Francisiella
E. coli
Yersinia
Vibrio
vaccination and route for B. abortus?
(antibody production)
S19 vaccine (SC)
vaccination and route for B. melitensis?
Rev-1 vaccine (SC)
RB51 vaccine route?
(cell-mediated immunity)
intraconjunctival route
most pathogenic Brucella?
B. melitensis (1-10 infectious dose)
3 places with NO brucella
- Japan
- Canada
- New Zealand
How long should you pasteurize milk to kill Brucella?
63C for 30 mins
only 1 with no CAT as accidental host
B. melitensis
only 1 with no CAMEL & HORSE as accidental host?
B. canis
