Brucellosis Flashcards

1
Q

can Brucellosis survive an acidic environment

A

NO (dies at pH 3.5)

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2
Q

Brucellosis survives cold environment

A

TRUE (preferred)

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3
Q

most widespread Brucellosis

A

B. abortus

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4
Q

Brucellosis spp that is NOT zoonotic

A

B. ovis (sheep)

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5
Q

which environments (2) do Brucella prefers

A

1) terrestrial
2) marine

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6
Q

Brucellosis where diff organs are affected

  • bone & joints
  • CNS
  • eyes
  • cardiovascular
  • respiratory
  • reproductive
A

chronic brucellosis

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7
Q

can Brucella cause abortion in humans as well?

A

YES

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8
Q

how many times can Brucella cause abortion in:

ruminants =
dogs =

A

ruminants = once (infertile na)
dogs = recurring

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9
Q

Brucella causes these 2 disease in HORSES

A
  1. Fistulous withers
  2. Poll evil
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10
Q

does Brucella cause death?

A

RARE

except in fetus

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11
Q

what organ can Brucella persist for longer period of time?

A

lymph nodes

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12
Q

is the animal infected with Brucella condemned/slaughtered agad?

A

YES

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13
Q

risk factor for Brucella?

young or old?
male or female?
hot or cold?
agroecology?

A

old
female
cold
dry climate

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14
Q

is Brucella a neglected zoonoses?

A

YES

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15
Q

Brucella is risk group?

A

3 (BSL 3)

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16
Q

gold standard for Brucellosis?

A

bacterial culture

17
Q

Brucella spp with rough LPS

[ ams ]

A

B.
abortus
melitensis
suis

18
Q

Brucella spp with smooth LPS

[ oc ]

A

B.
ovis
canis

19
Q

Serologic tests like:
1) Brucellin skin test
2) Rose Bengal tes

should be tested how many times?

20
Q

relies on “cell-mediated” immunity for antibody production

A

Brucellosis

21
Q

tests for Brucellosis that uses methylene blue (+ is uniform blue solution)

A

Milk Ring test

22
Q

treatment of Brucella for more than 8 y/o & adults?

A

doxycycline (PO)
gentamicin (IM)

23
Q

treatment of Brucella for less than 8 y/o ?

A

trimethoprim sulfamethoxazole (PO)
gentamicin (IV / IM)

24
Q

treatment of Brucella for pregant humans?

A

trimethoprim sulfamethoxazole (PO)
rifampicin (PO)

25
treatment of Brucella for animals?
long term antibiotics with • doxycycline • gentamicin
26
Brucella may cross react with [ FEYV ]
Francisiella E. coli Yersinia Vibrio
27
vaccination and route for B. abortus? (antibody production)
S19 vaccine (SC)
28
vaccination and route for B. melitensis?
Rev-1 vaccine (SC)
29
RB51 vaccine route? (cell-mediated immunity)
intraconjunctival route
30
most pathogenic Brucella?
B. melitensis (1-10 infectious dose)
31
3 places with NO brucella
1. Japan 2. Canada 3. New Zealand
32
How long should you pasteurize milk to kill Brucella?
63C for 30 mins
33
only 1 with no CAT as accidental host
B. melitensis
34
only 1 with no CAMEL & HORSE as accidental host?
B. canis