Disease in HUMANS Flashcards
• self-limiting
• asymptomatic
• but may cause fatal death (endocarditis CNS)
acute & chronic form
Brucellosis
• commonly affects CHILDREN
• Strep throat
• Scarlet fever
• Impetigo
Streptococcus pyogenes
Streptococcus not common in man
S. equi subsp. equi
Streptococcus common in newborn
S. agalactiae
STREPTO
Toxic shock-like syndrome
1) S. equi subsp. zooepidemicus
2) S. suis
STREPTO
sequelae of Strep throat
• may be self-limiting
Scarlet fever (Scarlatina)
STREPTO
• inhalation of droplets
• shares with sick person
• swollen vulva
• viral infection (symptomatic)
Strep throat
STREPTO
also caused by Staphylococcus aureus
• contact with fluid sores of skin
Impetigo
STREPTO
• death of fascia
• flesh-eating disease
• cutaneous route via cuts/wounds
also caused by
1. S aureus
2. Haemophilus
3. Vibrio
Necrotizing fascilitis
STREPTO
• cutaneous, superficial lesions
• Erysipelas — involve deeper tissue (lymph nodes draining)
• causative agent = S. pyogenes
Cellulitis (St. Anthony’s Fire)
causative agent = E. rhusiopathiae
• via pucture wounds
Erysipeloid
STREPTO
• fast disease progression
• cutaneous route
• common in geriatric px
Streptococcal toxic shock syndrome
Cholera is majorly caused by
biovar El Tor
low stomach acidity
Cholera
otitis media
Non-O1 (Non-O139 strains)
fatal septicemia
• biotype 1 & 3 — wound infection
• biotype 2 — farmed eels
Vibrio vulnificus
Vibrio ear & wound infection
V. aginolyticus
• non-invasive is self-limiting
• invasive
Shigellosis
• can be self-limiting if mild
severe cases:
• hemorrhagic colitis
• hemolytic uremic syndrome
Collibacillosis
a week after prodromal diarrhea
• acute kidney injury
• thrombotic thrombocytopenic purpura (TTP) in elders
Hemolytic Uremic Syndrome (HUS)
sex as risk factor
Yersiniosis
affects MALES more than females (Y. pseudotuberculosis)
Messenterial lymphadenitis
affects FEMALES more than males (Y. enterolytica)
Erythema nodosum
starts with Local Infection
• joint infections
• eye infection
• meningitis
• GIT problems
Pasteurellosis
Cutaneous Tuberculosis is also known as (3)
Tuberculosis Chancre
Tuberculosis cutis
Butcher’s wart
result of direct inoculation or endogenous spread of agent
Cutaneous tuberculosis
• Photophobia
• Drooping eyelids
• Untreated casesadescending paralysis
• Fatal within 24 hours
Botulism
common in drug abusers & cosmetic procedure
• anaerobic
• black tar heroin
Wound Botulism
commonly associated with
• honey
• dust
• Floppy baby syndrome
• sudden death
Infant botulism
adult intestinal colonization / toxemia
• affects older children & adults
• gastrointestinal surgery
• symmetrical flaccid paralysis
Foodborne botulism
inhalation or accidental injection of toxin
Iatrogenic botulism
higher infection dose of Foodborne botulism
Inhalation botulism
