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VPH 122 (3rd exam) > Shigellosis > Flashcards

Shigellosis Flashcards

1
Q

other name for Shigellosis?

A

Bacillary Dysentery

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2
Q

Shigellosis with 1 infectious dose?

A

S. sonnei

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3
Q

most prevalent Shigellosis?

A

S. dysenteriae

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4
Q

Shigellosis in developing country?

A

S. flexneri

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5
Q

Shigellosis is a gastrointestinal disease primarily in humans and what animals?

A

Non-human primates

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6
Q

Is antibiotic resistance common in Shigella?

A

YES

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7
Q

A healthy man with shigella drinks lots of water. What can happen in 4-7 days?

A

It can be self-limiting

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8
Q

most prevalent risk factor of Shigella in Thailand?

A

renting accomodation

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9
Q

What drug became resistant for Shigella in men who have sex with men and homeless people (Oregon)?

A

azithromycin for S. sonnei

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10
Q

Is Shigella in the Philippines?

A

YES (1980-1984)

S. flexneri (most prevalent)

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11
Q

Shigella invades these 2 epithelium:

A
  1. colonic
  2. rectal
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12
Q

2 spp that produces Shiga toxin

[ df ]

A

1) S. dysenteriae
2) S. flexneri

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13
Q

Infectious dose of Shigella?

A

10 - 200

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14
Q

Shedding span of Shigella?

A

4 weeks

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15
Q

Main route of transmission of Shigella?

A

feco-oral

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16
Q

most frequent acute kidney injury in young children

A

Hemolytic Uremic Syndrome

17
Q

disease caused by S. flexneri

A

Reactive Arthritis

18
Q

Disease caused by S. sonnei

A

Myocarditis

19
Q

What sample should be used in the microscopic exam of Shigella?

20
Q

Specific test for Shigella?

It occurs in 1 day (24hrs) but needs 2 days (48hrs).

A

Ornithine decarboxylase test

21
Q

pH of bromocresol purple

22
Q

pH of cresol red

A

pH 7.0 — 8.8

23
Q

Test for S. dysenteriae

24
Q

(3) Bacterial culture for Shigella

[ MXD ]

A
  1. MacConkey agar
  2. Xylose desoxychocolate agar
  3. Desoxychocolate Citrate agar
25
PCR for Shigella detects these 3 genes
ipaH virF virA
26
treatment for Shigella?
IV fluid
27
Is anti-motility drugs recommended for Shigella?
NO (contraindicated)
28
Infected person with Shigella should stay away for how many weeks in doing recreational water, food activity and other activities?
6 weeks at MOST
29
Can Shigella be killed by autoclaving?
YES (100C for 1hr)
30
(2) Drugs for children with Shigella?
1. Mecillinam 2. Ceftriaxone
31
1st line of antibiotics for Shigella?
Ciprofloxacin
32
Antibiotics for adults with Shigella?
Azithromycin
33
Other drugs recommended for shigella aside from the specific ones mentioned?
1. Fluoroquinolone 2. 3rd & 4th gen cephalosporin 3. sulfonamides 4. nalidixic acid
34
Can asymptomatic infection happen in Shigella?
YES
35
IP of Shigella?
12hrs — 3 days (ave: 3 days)
36
Lactose fermenters shigella?
EKCESS
37
Non-lactose fermenters shigella?
SPEMPYS

VPH 122 (3rd exam) (26 decks)

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