Treatment of Type 1 Diabetes Flashcards
what devices are available for secreting insulin?
syringe
disposable pen
reuasable cartridge pen
insulin infusion pump
what is the clinical presentation of hyperglycaemia?
thirst tiredness polyuria nocturia blurred vision weight loss fungal infections
what is the clinical presentation of hypoglycaemia?
pallor sweating tremor palpitations confusion nausea hunger cognitive dysfuntion eg confusion coma
what is basal insulin?
the first round of insulin secreted by the body in reacting to the body’s fasting glucose
what is post prandial insulin?
insulin secreted in relation to post meal glucose
what could be happening if the patient is spiking after a meal?
they aren’t taking their insulin properly
are analogues or pure human insulin?
analogues
what duration does levemir have?
long acting
what duration does novamix 30 have?
rapid acting analogue-intermediate
what duration does humulin 1 have?
intermediate acting
what duration does humulin m3 have?
short acting intermediate
what is the basal bolus regime of insulin aiming to replicate?
normal endogenous insulin production
what is the basal dose of insulin aiming to do?
keep resting glucose levels normal
what is the bolus does of insulin aiming to do?
keep post prandial glucose levels normal
how often is basal insulin takn?
once or twice depending on the insulin
how often is bolus insulin taken?
before insulin
what does prandial insulin need to be matched to?
carb intake
pre meal glucose
future activity eg exercise
how should you work out how many units someone needs of basal bolus insulin?
have 0,3 units per kg body weight
what would you give a 60kg male for his basal/bolus injections?
9 units basal before bed
3 units before each meal (9)
glucose target for T1DM’s pre meal?
4-7mmol/l
glucose target after a meal?
<10mol/l
how long does soluble insulin take to work?
30-60mins
when does soluble insulin peak in activity?
2-4hrs
when do insulin analgoes peak?
60-90 mins
