Treatment of Poisoning Flashcards
1
Q
What are the different management strategies
A
- prevent absorption ( activated characol/ whole body irrigation)
- antidote/chelation
- enhance elimintion (RRT/haemodialysis)
- supportive(maintain BP/ resp rate)
2
Q
How does activated charcoal work
A
- Has a massive SA; adsorb drug in GI tract therefore not allowing free drug to be absorbed.
3
Q
what is the dose of charcoal
A
single dose 50g
4
Q
what is activated charcoal inefffective in
A
- Elemental metals
- Insectides
- Cyanide
- Strong acid/ alkali
5
Q
what are the compliactions with charcoal
A
- Aspiration – if the vomit into the lungs when they are tired
- Obstruction – activated charcoal will sit in stomach; cause vomit which can cause aspiration
- Adsorbs therapy – it will take any drugs in stomach
6
Q
How does whole bowe irrigation work
A
- Induces liquid stool
2. Reduces bioavailability
7
Q
what do you give in whole bowel irrigation
A
Give 2L/hr of osmotically balances polyethylene glycol electrolyte solution orally
8
Q
what is whole body irrigation contraindicated in
A
- GI obstruction/ perforation
- Airway unprotected
- CVS instability
9
Q
what does the antidote naloxone work on
A
opioid
10
Q
what does the antidote n-acetylcysteine work on
A
paracetamol
11
Q
what does the antidote fomepizole work on
A
ethylene glycols
12
Q
what does the antidote deferoxamine work on
A
iron
13
Q
apsirin overdose presentation symtoms
A
- Nausea, tinnitus, flushed, restless, hyperventilation, pyrexia – inhibition of metabolic function
14
Q
what can aspirin toxicity cause
A
- Respiratory alkalosis and metabolic acidosis
15
Q
depressant overose presentation
A
- Recued consciousness, hypoventilation, needle marks, pinpoint pupils, death
