patches Flashcards
is transcutaneous local or systemic
local
is transdermal local or systemic
systemic
durogesic active drug
fentanyl
durogesic transdermal or not
transdermal
voltatrol or transdermal or transcutaneous
transcutaneous
voltarol active drug
diclofenac
advantages transdermal
Avoids hepatic first-pass metabolism (but skin could also metabolise drugs). • Non-invasive. • Extended release. • Readily applied and removable
disadvantages of transdermal
-
reservoir and matrix contains drug or controls drug release
contains drug
is rate limiting membrane matrix containing drug or controls drug release
controls drug release
function of polyacrylates
Adhesive
function of Polyester/ethylene vinyl acetate copolymer film
Backing film
function of Siliconized polyester
Proctetive release liner
function of Dipropylene glycol
Solvent
function of Hydroxylpropyl cellulose
matrix
function of dimeticone
matrix
function of silicone
adhesive
function of EVA
rate- controlling membrane
function of Polyethelene terephthalate film
backing film
function of fluoropolymer-coated polyester film
protective release liner
in stratum corneum is it lipophillic
lipophillic
the stratum corneum is the ……………………. diffusion barrier
rate-limiting
what are the different pathways
partitioning
diffusion
which pathway is in the same medium
diffusion