depot injections Flashcards

1
Q

long acting injectables have what kind of drug release profile

A

• Predictable drug-release profile during defined period of time

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2
Q

do long acting injectables have good patient compliance

A

yes

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3
Q

do long acting injectables have easy application

A

yes

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4
Q

what do long acting injectables avoid

A

first pass metabolism

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5
Q

advantages of SC

A

greater surface are for target injection sites, use of shorter needles, ease of self-administration, less discomfort, better safety profile – primary route for delivery of protein-based drugs – the volume of SC injection are usually limited to no more than 1-2 mL

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6
Q

types of long acting injectable formulaitons

A
  • oil based solution
  • drug suspension
  • polymer based
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7
Q

what are oil based solution suitable for

A
  • steroid esters

- IM route

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