Treatment of Endocrine disorders Flashcards
signs for a thyrotoxic crisis (4)
restlessness
tachycardia
tremor
hyperthermia
effects of iodine/iodine preps on the thyroid gland? (3)
- Decrease the vascularity of the thyroid gland
- increase the amount of bound (inactive hormone)
- inhibits the release of thyroid hormone into circulation
side effects of iodine/iodide preps
Derm and GI plus mucous membrane ulceration and metallic taste
Most common and preferred treatment for hyperthyroidism – over age 30
Iodine-131 (Radioactive Iodine)
what does Radioactive Iodine-131 emmit?
gamma rays and beta rays
half life of radioactive iodine
8 days
radioactive iodine - 131 as treatment for hyperthyroidism will ultimately lead to what?
hypothyroidism
what should be monitored in patients taking radioactive iodine 131?
radiation sickness (hematemesis, epistaxis, intense nausea, vomiting)
actions of growth hormone (3)
Promotes growth
Promotes protein synthesis
Carbohydrate metabolism
what does a deficiency of growth hormone result in?
short stature
what does a excess of growth hormone in childhood result in?
gigantism
what does a excess of growth hormone in adults result in?
acromegaly
what is somatropin used for
as a synthetic growth hormone
adverse effects of somatropin (5)
Hyperglycemia Hypercalciuria and renal calculi Hypothyroidism Antibody formation to GH Interaction with glucocorticoids
preferred drug for diabetes insipidus
desmopressin
what is vasopressin used as
a replacement for ADH
what is adrenal hormone excess known as?
Cushing’s syndrome
corticosteroid prototype
hydrocortisone
adverse effects of short-term gulcocorticoid therapy (4)
mild CNS + complaints
increased infections
poor wound healing
hyperglycemia
adverse effects of long-term gulcocorticoid therapy (5)
Cushingoid characteristics Adrenal suppression Osteopenia/Osteoporosis Fluid retention/Edema Electrolyte imbalance
describe fludrocortisone
Potent mineralocorticoid and has some glucocorticoid effects.
use for fludrocortisone
Mineralocorticoid replacement therapy in adrenocortical deficiency (Addison’s disease)
potential adverse effects of fludrocortisone (5)
Edema Hypertension CHF Cardiomegaly Hypokalemic alkalosis
when does levothyroxine start working?
within a few weeks
what is the effect of propanol on when treating grave’s disease?
decrease tremors and reduce heart beat
what does the thyroid preparation liothyronine consist of?
synthetic thyroid hormone T3
what does the thyroid preparation liotrix consist of?
Synthetic thyroid hormone T3-T4 combined
how does the thyroid behave in grave’s disease?
excessive thyroid hormone secretion
