Treatment of Endocrine disorders Flashcards

1
Q

signs for a thyrotoxic crisis (4)

A

restlessness
tachycardia
tremor
hyperthermia

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2
Q

effects of iodine/iodine preps on the thyroid gland? (3)

A
  • Decrease the vascularity of the thyroid gland
  • increase the amount of bound (inactive hormone)
  • inhibits the release of thyroid hormone into circulation
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3
Q

side effects of iodine/iodide preps

A

Derm and GI plus mucous membrane ulceration and metallic taste

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4
Q

Most common and preferred treatment for hyperthyroidism – over age 30

A

Iodine-131 (Radioactive Iodine)

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5
Q

what does Radioactive Iodine-131 emmit?

A

gamma rays and beta rays

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6
Q

half life of radioactive iodine

A

8 days

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7
Q

radioactive iodine - 131 as treatment for hyperthyroidism will ultimately lead to what?

A

hypothyroidism

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8
Q

what should be monitored in patients taking radioactive iodine 131?

A

radiation sickness (hematemesis, epistaxis, intense nausea, vomiting)

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9
Q

actions of growth hormone (3)

A

Promotes growth
Promotes protein synthesis
Carbohydrate metabolism

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10
Q

what does a deficiency of growth hormone result in?

A

short stature

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11
Q

what does a excess of growth hormone in childhood result in?

A

gigantism

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12
Q

what does a excess of growth hormone in adults result in?

A

acromegaly

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13
Q

what is somatropin used for

A

as a synthetic growth hormone

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14
Q

adverse effects of somatropin (5)

A
Hyperglycemia
Hypercalciuria and renal calculi
Hypothyroidism
Antibody formation to GH
Interaction with glucocorticoids
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15
Q

preferred drug for diabetes insipidus

A

desmopressin

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16
Q

what is vasopressin used as

A

a replacement for ADH

17
Q

what is adrenal hormone excess known as?

A

Cushing’s syndrome

18
Q

corticosteroid prototype

A

hydrocortisone

19
Q

adverse effects of short-term gulcocorticoid therapy (4)

A

mild CNS + complaints
increased infections
poor wound healing
hyperglycemia

20
Q

adverse effects of long-term gulcocorticoid therapy (5)

A
Cushingoid characteristics
Adrenal suppression
Osteopenia/Osteoporosis
Fluid retention/Edema
Electrolyte imbalance
21
Q

describe fludrocortisone

A

Potent mineralocorticoid and has some glucocorticoid effects.

22
Q

use for fludrocortisone

A

Mineralocorticoid replacement therapy in adrenocortical deficiency (Addison’s disease)

23
Q

potential adverse effects of fludrocortisone (5)

A
Edema
Hypertension
CHF
Cardiomegaly
Hypokalemic alkalosis
24
Q

when does levothyroxine start working?

A

within a few weeks

25
Q

what is the effect of propanol on when treating grave’s disease?

A

decrease tremors and reduce heart beat

26
Q

what does the thyroid preparation liothyronine consist of?

A

synthetic thyroid hormone T3

27
Q

what does the thyroid preparation liotrix consist of?

A

Synthetic thyroid hormone T3-T4 combined

28
Q

how does the thyroid behave in grave’s disease?

A

excessive thyroid hormone secretion