More study for Exam 2 Flashcards
Dantrolene adverse effects
Weakness, drowsiness Hepatic toxicity
what type of drug is propranol?
a beta blocker
Mood-Stabilizing Anticonvulsants
Valproic acid Carbamazepine Lamotrigine
Monoamine Oxidase Inhibitors (MAOIs) (4)
Phenelzine Selegiline Isocarboxazid tranylcypromine “PIST”
Serotonin/Norepinephrine Reuptake Inhibitors (SNRIs) (2)
Venlafaxine (Effexor) Duloxetine (Cymbalta)
what can provide immediate relief of anxiety
Benzodiazepines (such as clonazepam and alprazolam)
signs of lithium toxicity
polydipsia, slurred speech, and fine hand tremors
what is important to assess after the administration of an anti-psychotic?
The orthostatic blood pressure measurements
what drug class is caffeine in?
Methylxanthines
Methylphenidate usage
Used for attention-deficit/hyperactivity disorder (ADHD)
adverse effects of levodopa
- Cardiac arrhythmias
- Darkened urine and sweat
- Can activate malignant melanoma
How should Levadopa be taken?
with food to decrease nausea and vomitting
what vitamin may levadopa have an interaction with
vitamin B6
What should be monitored for in patients on medication for Parkinson’s?
- Inform/monitor for cardiac problems
- Monitor for orthostatic hypotension
- Monitor for signs of psychosis
- May need drug holiday
what drug is combined with levadopa to inhibit levadopa’s metabolism?
Entacapone
what is the basic action of anticholinergic agents
Block the action of acetylcholine
2 anticholinergic agents
- Benztropine
- Trihexyphenidyl
nParkinson’s disease reflects an imbalance between inhibitory and stimulating activity of nerves in the…?
Basal ganglia
Adverse effects of Alzhiemers drug therapy
- GI –stimulation leading to nausea & vomiting, diarrhea and stomach irritation
- Dizziness
- Headache
What surgical treatment of parkinson’s can also be done?
Surgical interventions involving basal ganglia
what type of agonist is pramipexole?
dopamine agonist
adverse effects of pramipexole
- nausea,
- dizziness,
- daytime
- somnolence
- , insomnia
The big gun AED known to cause changes in personality
Levetiracetam
3 drugs used for therapy for Spasticity
- Baclofen
- Diazepam
- Dantrolene
Adverse effects of Baclofen
- CNS depressant
- GI symptoms—nausea, constipation
- Urinary retention
How do Centrally Acting Muscle Relaxants work?
Work in the CNS to interfere with the reflexes that are causing the muscle spasm
prototype for barbiturates
phenobarbital
when does buspirone start working?
no quick acting like other benzodiazepines
Onset one week with full effect 2-6 weeks not a prn medication
Adverse effects for buspirone
– Dizzy
– Nausea
– Headache
lDrug of choice to treat insomnia and anxiety
Benzodiazepines
what are depot drugs
long-acting, injectable formulations used for long-term maintenance
What are some extrapyramidal symptoms?
Acute Dystonia
Parkinsonisms
Akathisia
tardive dyskinesia
Rare but potentially fatal complication of inhalation anesthetics?
Malignant Hyperthermia
what is an important consideration when administering ergotamine?
Do not use within 24 hours of triptans
how long does it take to develop a tolerance the the adverse effect of orthostatic hypotension?
2-3months
what is a late side effect of FGAS?
Tardive dyskinesia
Ultrashort acting Barbiturate
thiopental
Short to intermediate acting barbiturate
secobarbital
Long acting barbiturate
phenobarbital