Treatment myleoid and lymphoid malignancies Flashcards
1
Q
TKI’s
A
For CML
Inhibit ATP by binding on the ADP bindingpocket
2
Q
1st generation TKI
A
Imatinib
3
Q
2nd generation TKI
A
clasatinib, nilotinib
4
Q
AlloSct
A
CML: when there is no response to TKI, there is mutation ADP bindingpocket, TKI intolarance
AML
5
Q
Remission indcuction therapy
A
AML
High dose of chemo with cytarabine, anthraclycine
6
Q
AutoSct
A
AML
7
Q
Rituximab
A
Anti CD20 antibody
Follicular lymphoma
8
Q
Treatment of diffuse B-cell lymphoma
A
Combination of chemo, immunotherapy and prednison
9
Q
Lymphomas in one anatomic region
A
Radiation
10
Q
Targeted therapy
A
Lymphomas with activated oncogenes
11
Q
Venetoclax
A
Targeted therapy for BCL2
12
Q
B-cell lymphomas
A
chemo and retuximab