Treatment myleoid and lymphoid malignancies Flashcards

1
Q

TKI’s

A

For CML

Inhibit ATP by binding on the ADP bindingpocket

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2
Q

1st generation TKI

A

Imatinib

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3
Q

2nd generation TKI

A

clasatinib, nilotinib

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4
Q

AlloSct

A

CML: when there is no response to TKI, there is mutation ADP bindingpocket, TKI intolarance
AML

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5
Q

Remission indcuction therapy

A

AML

High dose of chemo with cytarabine, anthraclycine

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6
Q

AutoSct

A

AML

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7
Q

Rituximab

A

Anti CD20 antibody

Follicular lymphoma

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8
Q

Treatment of diffuse B-cell lymphoma

A

Combination of chemo, immunotherapy and prednison

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9
Q

Lymphomas in one anatomic region

A

Radiation

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10
Q

Targeted therapy

A

Lymphomas with activated oncogenes

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11
Q

Venetoclax

A

Targeted therapy for BCL2

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12
Q

B-cell lymphomas

A

chemo and retuximab

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