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MOD2 > Pharmacotherapy 3 > Flashcards

Pharmacotherapy 3 Flashcards

1
Q

Protein kinase inhibitors

A 
Imatinib
Erlotinib
Sunitinib
Everolimus
Temisirolimus
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2
Q

Imatinib

A

Protein kinase inhibitor
GI tumors
CML

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3
Q

Erlotinib

A

Protein kinase inhibitor

Metastasized NSCLC

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4
Q

Sunitinib

A

Protein kinase inhibitor
GI tumors
Hepatocellular carcinoma
Clear cell kidney carcinoma

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5
Q

Everolimus

A

Protein kinase inhibitor, mTOR-inhibitor

mediate- high risk metastatic renal cell cancer

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6
Q

Temisirolimus

A

Protein kinase inhibitor, mTOR-inhibitor

Low risk metastatic renal cell cancer

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7
Q

Bisphosphonates working

A

Attach to bone crystals > are absorbed by osteoclasts > induce apoptosis > freeze cycle of bone remodelling

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8
Q

Bisphosphonate medicine

A

Pamidronic acid

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9
Q

Pamidronic acid

A

Bisphosphonate
Prevention of osteoporosis
Treatment of hypercalcemia
Metastases and mamma carcinoma

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10
Q

Low risk emesis

A

Metoclopramide

Dexamethasone

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11
Q

Moderate risk emesis

A

5HT3-antagonist + dexamethasone

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12
Q

Strong risk emesis

A

Predose of 5HT3-antagonist + dexamethasone

Then dexamethasone + metoclopramide

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13
Q

Severe risk of emesis + cisplatin

A

Predose of 5HT3 antagonist + dexamethasone

Then dexametahsone + metoclopramide or aprepitant

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MOD2 (23 decks)

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