Proteins Flashcards
1
Q
RAS active
A
Bound to GTP
Activates MAP > regulation of gene expression
2
Q
PARP-1
A
DNA damage sensing in BER
3
Q
RAD-51
A
Accumulates during HR
4
Q
E-cadherin
A
Binds B-catenin
5
Q
B-catenin
A
Induces transpcription of genes in nucleus
6
Q
MMP’s
A
Produces enzymes which digest the ECM
7
Q
Ingegrins
A
Tell cell if its in right context or not
8
Q
CAF
A
Produce TGF-B
9
Q
HIF-alpha
A
Stimulation of angiogenesis, glycolysis, support of cell survival
10
Q
Ras inactive
A
Bound to GDP
11
Q
GEF
A
inactive RAS to active RAS
12
Q
GAP
A
active RAS to inactive RAS
13
Q
CKD
A
Fosforylation of Rb > afgifte restrictiepoint
14
Q
E2F
A
Transcritptiefactor
15
Q
p16
A
Inhibits CDK
