Signatures

Question 1

Signature 1

Answer 1

Found in almost all cancers

Spontaneous deamination of C

Question 2

Signature 2

Answer 2

Found in cervix cancer

Question 3

Signature 4

Answer 3

Found in head & neck, liver, esophageal cancers and lung carcinomas
Associated with smoking
A–>C

Question 4

Signature 7

Answer 4

Skin cancers
Associated with UV
CC–>TT

Question 5

Signature 11

Answer 5

Melanomas, glioblastomas

C–> T

Question 6

Signature 13

Answer 6

Breast cancer