Pharmacotherapy 1 Flashcards
Cytostatics
Alkylating agents
Antimetabolites
Antimitotics
Topoisomerase inhibitors
Alkylating agents working and medicine
Inhibition of DNA replication
Cisplatin
Carboplatin
Cyclophosphamide
Cisplatin
Alkylating agent
Testis, bladder, ovary, cervix and lung
Carboplatin
Alkylating agent
Ovary carcinoma
In CRC in combination with 5-FU
Cyclophosphamide
Alkylating agent
Leukemia, prostate, breast
Antimetabolities working and medicine
During S-phase
Methotrexate
5-FU
Gemcitabine
Methotrexate
Antimetabolite
Breast, placenta, bladder, leukemia
5-FU
Antimetabolite
Colon, stomach, breast, prostate, epithelial carcinoma of head and neck
Gemcitabine
Antimetabolite
Carcinomas
Antimitotics working and medicine
Inhibit microtuble formation
Vinblastine
Vincristine
Vinorelbine
Vinblastine
Antimitotic
Lymphomas, germ cell and carcinomas
Vincristine
Antimitotic
Lymphomas, leukemias, pediatric tumors
Vinorelbine
Antimitotic
Metastasized BRC when other therapies failed
Topoisomerase inhibitors working and medicine
Prevent DNA repair and induce DNA damage
Topotecan
Etoposide
Doxorubicin
Etoposide
Topoisomerase inhibitor
Testis, bronchus carcinoma, leukemias