Transplantation and Rejection Flashcards

1
Q

Allograft

A

transplantation between non-genetically identical members of the same species

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2
Q

Importance of MHC Class I tissue matching

A

suppressing allograft transplantation rejection

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3
Q

Three MHC I genes

A

HLA-A
HLA-B
HLA-C

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4
Q

Indirect Allorecognition Rejection

A

originate from Host Immune System

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5
Q

Direct Allorecognition Rejection

A

originate from Donor Graft Tissue

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6
Q

Main function of immunosuppressants

A

block production/function of Interleukin 2

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7
Q

Daclizumab

Basiliximab

A

IL-2 Receptor Antagonists

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8
Q

Tacrolimus

Cyclosporine

A

Calcineurin inhibitors

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