Transplantation and Rejection Flashcards
1
Q
Allograft
A
transplantation between non-genetically identical members of the same species
2
Q
Importance of MHC Class I tissue matching
A
suppressing allograft transplantation rejection
3
Q
Three MHC I genes
A
HLA-A
HLA-B
HLA-C
4
Q
Indirect Allorecognition Rejection
A
originate from Host Immune System
5
Q
Direct Allorecognition Rejection
A
originate from Donor Graft Tissue
6
Q
Main function of immunosuppressants
A
block production/function of Interleukin 2
7
Q
Daclizumab
Basiliximab
A
IL-2 Receptor Antagonists
8
Q
Tacrolimus
Cyclosporine
A
Calcineurin inhibitors