Bacteria and Infection Flashcards
What is linked to... toxin mediated disease scalded skin syndrome food poisoning toxic shock
Staph. aureus
capsule protein A fibronectin binding protein cytolytic exotoxins Panton-Valentine leukocidin
S. aureus pathogenicity factors (5)
pneumoniae
viridans
alpha-haemolytic streps
pyogenes A
agalactiae B
beta-haemolytic streps
gamma-haemolytic streps
enterococcus
What is linked to... pharyngitis scarlet fever cellulitis necrotising fasciitis sepsis
strep. pyogenes
Difference between Gram+ve and Gram-ve bacteria
gram-ve has inner and outer membrane
Extrinsically acquired resistance -
Transformation
transfer of cell free DNA that contains antibiotic resistance genes
Extrinsically acquired resistance -
Transduction
transfer of bacterial DNA that contains antibiotic resistance via a bacteriophage
Extrinsically acquired resistance -
Conjugation
transfer of bacterial and plasmid DNA between mating cells
Extrinsically acquired resistance -
Propagation
proliferation of antibiotic resistant bacteria
What are the antibiotic targets?
cell wall synthesis protein synthesis (30S & 50S, tRNA) cytoplasmic membrane structure folic acid metabolism DNA gyrase RNA elongation