Bacteria and Infection Flashcards

1
Q
What is linked to... 
toxin mediated disease
scalded skin syndrome
food poisoning
toxic shock
A

Staph. aureus

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2
Q
capsule
protein A
fibronectin binding protein
cytolytic exotoxins
Panton-Valentine leukocidin
A

S. aureus pathogenicity factors (5)

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3
Q

pneumoniae

viridans

A

alpha-haemolytic streps

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4
Q

pyogenes A

agalactiae B

A

beta-haemolytic streps

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5
Q

gamma-haemolytic streps

A

enterococcus

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6
Q
What is linked to...
pharyngitis
scarlet fever
cellulitis
necrotising fasciitis
sepsis
A

strep. pyogenes

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7
Q

Difference between Gram+ve and Gram-ve bacteria

A

gram-ve has inner and outer membrane

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8
Q

Extrinsically acquired resistance -

Transformation

A

transfer of cell free DNA that contains antibiotic resistance genes

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9
Q

Extrinsically acquired resistance -

Transduction

A

transfer of bacterial DNA that contains antibiotic resistance via a bacteriophage

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10
Q

Extrinsically acquired resistance -

Conjugation

A

transfer of bacterial and plasmid DNA between mating cells

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11
Q

Extrinsically acquired resistance -

Propagation

A

proliferation of antibiotic resistant bacteria

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12
Q

What are the antibiotic targets?

A
cell wall synthesis
protein synthesis (30S & 50S, tRNA)
cytoplasmic membrane structure
folic acid metabolism
DNA gyrase
RNA elongation
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