Trans - Autonomic Nervous System Flashcards
primary functional unit of ANS
2 neuron chain system
postganglionic fibers of ANS end in
varicosities
preganglionic fiber - with or without myelin
myelinated
postganglionic fiber - with or without myelin
unmyelinated
preganglionic fiber - receptor
nicotinic
postganglionic fiber - receptor
muscarinic
preganglionic fiber - axon type
type B
postganglionic fiber - axon type
type C
ratio of preganglionic:postganglionic fibers in sympathetic NS
1:5
preganglionic fibers of sympathetic NS arise from
roots T1-L2
thoracolumbar division
sympathetic NS preganglionic
largest cervical ganglion
superior cervical;
what system has short preganglionic and long postganglionic fibers
sympathetic NS
what system has long preganglionic and short postganglionic fibers
parasympathetic NS
what system innervates adrenal medulla
sympathetic
what cells of the adrenal medulla are stimulated by the ANS
chromaffin cells
chromaffin cells secrete:
epinephrine and norepinephrine
epinephrine acts on what receptors
alpha 2, beta 2
norepinephrine acts on what receptors
alpha 1, beta 1, beta 3
the locus coeruleus contains neurons that have
epinephrine
epinephrine has a greater effect in stimulating alpha or beta receptors?
beta
norepinephrine has a greater effect in stimulating alpha or beta receptors?
alpha
known as the craniosacral division
parasympathetic ANS
ratio of preganglionic:postganglionic fibers in parasympathetic NS
1:1
ionotropic receptor in parasympathetic ANS
nicotinic
m1 receptor - function
secretion of gastric acid
m2 receptor - function
most abundant receptor, in smooth muscles
m3 receptor - function
smooth muscles
m4 receptor - function
autonomic ganglia
m5 receptor
spinchter of pupil, esophagus, parotid gland
exceptions to the rule that Ach is used only by parasympathetic effectors
- anatomically sympathetic postganglionic neurons that innervate sweat glands
- anatomically sympathetic postganglionic neurons that innervate blood vessels in muscles
systemic arterial tone - sympathetic or parasympathetic
sympathetic
GIT - sympathetic or parasympathetic
parasympathetic
heart - sympathetic or parasympathetic is dominant
parasympathetic
why does the sympathetic system have more widespread effects?
- more divergence
- lasts longer
- neurotransmitter used is not easily degraded
neurotransmitter in parasympathetic system
Ach
neurotransmitter in sympathetic system
epinephrine, norepinephrine
system that promotes survival in crisis state
sympathetic
system that promotes survival in safe state
parasympathetic
baroreceptors synapse with which nucleus
nucleus tractus solitarius
function of parasympathetic
rest and digest
- conservation and restoration of body energy
- waste elimination
- decrease in heart rate (which will decrease energy demand)
- increase in GIT activity (restoration of energy)
function of sympathetic
response to stress or danger (fight or flight)
ganglionic cholinergic receptor
m1
cardiac cholinergic receptor
m2
bronchial, glandular, cholinergic receptor
m3
only adrenergic receptor that uses IP3/DAG for 2nd messenger
alpha 1
only cholinergic receptor that uses IP3/DAG for 2nd messenger
m1
muscarinic receptor - ionotropic or metabotropic
metabotropic