Toxins Flashcards

1
Q

what do toxins or poisons do for the bacteria

A

enhance their virulence

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2
Q

what are the two types of toxins

A

endotoxin and exotoxin

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3
Q

what toxin causes system wide effects such as fever and shock

A

endotoxin

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4
Q

what toxin is stable at high heats

A

endotoxin

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5
Q

what toxin is unstable or heat-labile and denatures at high heat

A

exotoxin

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6
Q

what toxin is produced but NOT secreted from dead gram - bacteria

A

endotoxin

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7
Q

what toxin is derived from lipopolysaccharide found in the cell walls of gram - bacteria

A

endotoxin

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8
Q

what are common side effects of endotoxins

A

fever and shock

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9
Q

what are the two exceptions to exotoxins that are NOT heat-labile but instead are heat stable

A

staphylococcal enterotoxin

e coli toxin

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10
Q

toxoids are specific to which toxins

A

exotoxins

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11
Q

what is a toxoid

A

a toxin that has been denatured by formaldehyde

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12
Q

what do toxoids do

A

stimulate immunity

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13
Q

what toxin is tissue specific and affects those tissues in particular

A

exotoxins

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14
Q

what are 3 exotoxins and their examples of

affecting specific tissues which demonstrates tissue specificity

A

exotoxin - tissue
tentanospasmin - nerve
botulinin - muscle
diphtheria toxin - connective tissue

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15
Q

beta hemolytic strep contains what enzyme that adds to its virulence

function

A

streptokinase

dissolves clots which the body uses to wall off the organisms from spreading

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16
Q

staph contain what enzyme that adds to its virulence

A

coagulase - catalyzes formation of fibrin from fibrinogen - fibrinogen broken into fibrin

hemolysin - breaks down RBCs - also called alpha toxin

17
Q

staph or strep contain what enzyme that adds to its virulence

A

leukocidin

exotoxin that kills WBCs and phagocytes

18
Q

staph, strep, and clostridia contain what enzyme that adds to its virulence

A

hyaluronidase

breaks down tissue cement of hyaluronic acid
facilitates dissemination of microorganisms