Hypersensitivity Reactions

Question 1

Hypersensitivity Type 1 name

Answer 1

anaphylatic (immediate)

Question 2

Hypersensitivity Type 1 time frame

Answer 2

rapid

15-30 sec

Question 3

Hypersensitivity Type 1 examples

Answer 3

allergy induced bronchial asthma

bee sting

hayfever

Question 4

Hypersensitivity Type 1 ab and cells

Answer 4

IgE
mast cells
basophils

Question 5

Hypersensitivity Type 2 name

Answer 5

cytotoxic

Question 6

Hypersensitivity Type 2 time frame

Answer 6

mins to hours

Question 7

Hypersensitivity Type 2 examples

Answer 7

good pasteurs -
caused by GABHS (lung and kidney)

erythroblastosis fetalis - coombs anemia

blood transfusion

myasthenia gravis

graves disease - hyperthyroidism

Question 8

Hypersensitivity Type 2 ab and cells

Answer 8

IgG
targests cell for phagocytosis

two things aka type 2
antigen + antibody

Question 9

Hypersensitivity Type 3 name

Answer 9

immune complex mediated

Question 10

Hypersensitivity Type 3 time frame

Answer 10

3-10 hours

Question 11

Hypersensitivity Type 3 examples

Answer 11

glomerulonephritis
SLE
RA

arthus = local necrosis
serum sickness = systemic

Question 12

Hypersensitivity Type 3 ab and cells

Answer 12

IgG and complement

3 things aka type 3
antigen + ab + complement

Question 13

Hypersensitivity Type 4 name

Answer 13

delayed type hypersensitivity

or cell mediated or cellular

Question 14

Hypersensitivity Type 4 time frame

Answer 14

48 hours

Question 15

Hypersensitivity Type 4 examples

Answer 15

TB
contact dermatitis - poison ivy/oak
transplant rejection via MHC

Question 16

Hypersensitivity Type 4 ab and cells

Answer 16

t cell

lymphocytes