RNA Viruses Flashcards
all RNA virus are __ stranded except __
single stranded
except Reo/rota group which is double stranded
all negative single stranded RNA viruses are ___ and ___
helical and enveloped
what are the 3 naked RNA viruses
Calici, Pico, and Reo RNA viruses
CPR
all hepatitis viruses are __ except which?
RNA
except hepatitis B - which is DNA
all hepatitis viruses are spread by ___ except which?
and how are they spread?
oral fecal route
except B and C - spread by sex, blood transfusions, or IV drugs
what do hepatitis viruses cause
jaundice fever anorexia vomiting tender hepatomegaly
what virus causes hepatitis C
Flavivirus
what is the most common transmission of hepatitis C
IV drug use and tattoos - 40%
sex and blood transfusion - 20% f
what is hepatitis C characterized by
carrier state
cirrhosis
primary hepatocellular carcinoma**
what virus causes hepatitis A
Picornavirus
how is hepatitis A transmitted
oral-anal route
oral-fecal route
what causes hepatitis D
hepatitis B infection
hepatitis D is defective unless accompanied with hepatitis B infection
what virus causes hepatitis E
calicivirus
how is hepatitis E transmitted
oral-anal route
oral-fecal route
(traveling)
human immunodeficiency virus is caused by what
retrovirus - lentivirus subfamily
how is HIV transmitted
sex and blood transfusion
how does HIV lead to AIDS
the retrovirus destroys the CD4 T helper cells
what are the four stages of HIV/AIDS
flu like illness - acute
feeling fine - latent
falling CD4 T cell count causes recurrent oppurtunistic infections (such as cryptococcus meningitis, cytomegalovirus retinitis, candidiasis, cryptosporidium diarrhea)
pneumocysitis jiroveci pneumonia - final crisis
what are other names from measles
rubeola or 1st disease
what virus causes measles
paramyxovirus
how is measles spread
aerosol droplets
what does measles cause
koplik spots - white lesion surrounded by red ring around buccal mucousa
coryza - inflammation of mucous membrane in nose
conjunctivitis
maculopapular erythematous rash
syncytia - giant multinucleated cells
what virus causes mumps
paramyxovirus
how is mumps transmitted
direct contact and aerosol droplets
what does mumps cause
parotitis - parotid gland enlargement*
pancreatitis
orchitis (inflammation of testicle)
what are other terms for Rubella
german measles
or
3rd disease
what virus causes rubella
togavirus - rubivirus specifically
how is rubella transmitted
aerosol droplets
what does rubella cause
sore throat
cervical lymphadenopathy
maculopapular erythematous rash
congenital infection in kids in first 10 weeks
what virus causes influenza
orthomyxovirus
what does influenza cause
fever
sorethroat
severe myalgia
what virus causes the common cold in adults and gastroenteritis in infants
coronavirus
how is common cold transmitted
aerosol droplets
what does the common cold cause
fever
sorethroat
runny eyes
runny nose
what virus causes a upper respiratory tract infection
rhinovirus of picornavirus family
what does URTI cause
runny eyes
nose
sorethroat
fever
what virus causes the infant disease known as croup
parainfluenza virus - paramyxovirus
what does croup cause
braking cough
stridor - whistling on breathing
hoarseness
what virus causes childhood dysentery (bloody diarrhea)
coxsackie virus of the picoRNA family
what virus causes rabies
rhabdovirus
what is present in brain tissue in a rabies patient
negri bodies
what shape is the rhabdo virus that causes rabies
bullet shaped
how is rabies transmitted
raccoons, bats, and skunk bites are more common in US than dog bites
what does rabies cause
hydrophobia dysphagia agitation paralysis coma
what virus causes poliomyelitis
picornavirus
what does poliomyelitis cause
flaccid muscle paralysis (LMN sign)
due to destruction of ventral or anterior horn cell damage
what does “ARBO” mean in the term ARBO viruses
arthropod borne
what are ARBO viruses caused by?
arthropods obviously, but what virus specifically?
exceptions?
flavivirus (w and ve encephalitis toga ??)
except california encephalitis which is bunya virus
what are 4 ARBO viruses
DEWY dengue fever encephalitis west nile fever yellow fever
how is encephalitis causing viruses spread? what vector?
mosquitos
what are the 3 different kinds of encephalitis?
what are the viruses that cause them?
western encephalitis - flavivirus /togavirus ??
venezuelan equine encephalitis - flavivirus /toga ??
california encephalitis - bunya virus
what virus causes yellow fever?
and what is its vector
flavivirus
aedes aegypti mosquito
(note: same vector and virus as dengue fever but different symptoms - no jaundice)
what are the symptoms of yellow fever
fever and juandice
what virus causes west nile fever?
and what is its vector?
flavivirus
cullex pipiens mosquito
what virus causes dengue fever?
and what is its vector?
flavivirus
aedes aegypti mosquito
(note: same vector and virus as yellow fever but different symptoms - jaundice)
what are the 4 categories of RNA viruses
positive sense
negative sense
ambisense
double stranded
which RNA virus is acid labile
rhinovirus
what virus is the leading cause of the common cold
rhinovirus
coronavirus
SARS stands for what
associated with what virus
severe acute respiratory syndrome
coronavirus
norwalk virus is what kind of virus
calicivirus
how does someone get infected by norwalk virus
contaminated food
fecal oral route
what does norwalk virus cause
gastroenteritis
what is another term for breakbone fever
dengue fever
which virus has club shaped surface projections that give its appearance
coronavirus
how is yellow and dengue fever transmitted to humans
monkeys to mosquitos to humans
what fever/virus causes eosinophilic hyaline masses called councilman bodies in the infected liver cells
yellow fever - ARBOvirus
what is the leading cause of arboviral encephalitis in the US
west nile virus
echoviruses are what type of viruses
picornavirus
echoviruses cause what
meningitis, skin rash, heart disease
what viruses contain hemagglutinin neuraminidase
paramyxoviruses
what type of virus is ebola virus
filovirus
what does ebola cause
african hemorrhagic fever then death
what is caused by a negative reaction to aspirin when taken for a viral infection such as influenza
reyes syndrome
causes fatty liver and encephalopathy
influenza contains what specifically that makes it necessary to vaccine yearly
antigenic shift or drift
drift - small mutation
shift - big mutation
causes flu so thats why we take vaccine yearly