DNA Viruses Flashcards

1
Q

all viruses are ___ except for 7 which are ___

A

all viruses are RNA

except 7 which are DNA

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2
Q

what are the 7 that are DNA viruses

A

3 are enveloped - hepa, herpes, pox

3 are naked - papilloma, adeno, papova
(need to get naked to get PAP smear)

1 is single stranded - parvo

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3
Q

all DNA viruses are __ stranded

1 exception?

A

DNA viruses =double stranded

except parvovirus which is single stranded

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4
Q

all DNA viruses are __ in shape

1 exception?

A

DNA viruses = icosahedral

except “pox” viruses which are complex BRICK shaped

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5
Q

what virus causes cold sores or fever blisters?

what virus causes painful genital ulcers?

A

herpes simplex virus 1

herpes simplex virus 2

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6
Q

how are herpes simplex viruses 1 and 2 spread?

A

direct contact

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7
Q

chicken pox is also known as

A

herpes zoster
or
varicella zoster virus

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8
Q

herpes zoster and chicken pox are also known as what HHV type

A

herpes virus type 3

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9
Q

how is chicken pox or herpes zoster spread?

A

aerosol droplets

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10
Q

what is the adult form of chicken pox

A

shingles

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11
Q

what is human herpes virus type 4?

HHV4

A

mononucleosis
or
Epstein barr virus

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12
Q

how is mononucleosis spread

A

kissing

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13
Q

what are symptoms of mononucleosis?

A

sore throat
fatigue
cervical lymphadenopathy
hepatosplenomegaly

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14
Q

what cells are present in mononucleosis

A

Downey cells which are atypical lymphocytes

IgM heterophile antibodies

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15
Q

what test is positive in mononucleosis

A

Paul Bunnel test

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16
Q

what 2 diseases can mononucleosis lead to or cause

A

burkitts lymphoma
or
nasopharyngeal carcinoma

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17
Q

what is human herpes virus 5

HHV5

A

cytomegalovirus

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18
Q

what does cytomegalovirus cause in immunocompromized patient? neonates?

A

interstitial pneumonia in immunocompromized patients

congenital abnormalities, brain calcification, and hepatosplenomegaly in neonates

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19
Q

what disease is caused by human herpes virus 6/7?

HHV6 also called 7 sometimes

A
Exanthema subitum 
or 
Roseola Infantium 
or 
6th Disease
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20
Q

what is known as 6th disease

A

Exanthema subitum
or
Roseola Infantium

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21
Q

what does exanthema subitum cause

A

sudden rash after a fever in children
(roseola infantium - kids rash)
febrile seizures in children

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22
Q

what disease is caused by herpes virus 8

A

kaposi sarcoma

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23
Q

what symptoms does herpes virus 8 or kaposi sarcoma cause

A

purplish oral or skin lesions in AIDS patients

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24
Q

what is also known as 5th disease

A

slapped cheek syndrome
or
erythema infectiosum

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25
Q

what virus causes slapped cheek syndrome

A

parvovrius type b19

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26
Q

what does parvovirus type b19 cause

A
slapped cheeked syndrome 
or 
erythema infectiosum 
or 
5th disease
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27
Q

erythema infectiosum or 5th disease causes what symptoms

A

red rash on face after fever

slapped cheek syndrome

28
Q

how is hepatitis B spread

A

blood or sex

29
Q

what virus causes hepatitis B

A

hepatitis B DNA virus

30
Q

what are the symptoms of hepatitis B

A

jaundice and tender hepatomegaly

31
Q

what virus causes viral conjunctivitis

A

adenovirus

32
Q

what virus causes pink eye

A

adenovirus

33
Q

how is adenovirus spread to develop pink eye or viral conjunctivitis

A

aerosol droplets

34
Q

what is pink eye also known as

A

epidemic viral conjunctivitis

35
Q

what virus causes smallpox

A

pox virus - variola virus specifically

36
Q

how is pox virus spread to develop small pox

A

aerosol droplets

37
Q

what are present in the epidermis of small pox patients

A

guarneri inclusion bodies

38
Q

when was small pox irradicated

A

1976

39
Q

what virus causes human papilloma virus

A

papova virus

40
Q

what is HPV spread

A

direct contact or sex

41
Q

which types of HPV are associated with genital warts and cervical cancer

A

HPV 16 and 18

42
Q

which types of HPV are associated with warts on hands and feet

A

HPV 1 and 4

43
Q

what virus causes molluscum contagiosum

A

pox virus

44
Q

how does pox virus spread to cause molluscum contagiosum

A

direct contact

45
Q

what symptoms does molluscum contagiosum cause

A

papular lesions with central indentation or umbilication

wartlike papular lesions on face, arms, back, buttocks, and genitals and resolves spontaneously after couple months

STD with papular lesions that ulcerate and mimic herpes

46
Q

what DNA virus causes pharyngitis

A

adenovirus

47
Q

what DNA virus causes meningitis in AIDS patients

A

CMV

48
Q

what DNA virus causes JC and BK viruses which cause demyelination and UTI/kidney problems

A

polyomavirus

49
Q

papovaviruses are divided into what two groups

A

papillomavirus

polyomavirus

50
Q

what does JC virus cause

A

progressive multifocal leukoencephalopathy

51
Q

what does BK virus cause

A

UTI and kidney problems

52
Q

what is the only hepatitis that is DNA in origin

A

HepB

53
Q

which DNA viruses latently infects neurons

A

herpesvirus

54
Q

what vaccine is given to prevent HPV

A

gardasil

55
Q

what is the acute form of varicella zoster

what is the latent form

A

chickenpox - acute

shingles - latent

56
Q

what strain of varicella zoster is used in vaccines to prevent chickenpox and diminish shingles recurrence

A

Oka strain

57
Q

what DNA virus is associated with owls eye intranuclear inclusion bodies

A

cytomegalovirus

appearance due to swelling of infected cells

58
Q

what causes a heterophile negative mononucleosis

what causes a heterophile positive mononucleosis

A

CMV

EBV

59
Q

EBV infects what cells

A

B lymphocytes

causes proliferation and transformation

60
Q

how do we diagnose EBV

A

mononucleosis spot test

61
Q

how is kaposi sarcoma transmitted

A

sexual contact

62
Q

HHV 6/7 infects what cells

A

T lymphocytes

63
Q

guarnieri bodies are found in what viruses

whats another name for these bodies

A

pox virus (small pox specifically)

eosinophilic inclusion bodies

64
Q

what are the different pox viruses

A

variola virus - causes small pox

vaccinia virus - cause mild disease - used in small pox vaccine

molluscum contagiosum virus

65
Q

what virus causes 5th disease

A

paravovirus b19

66
Q

what virus causes erythema infectiosum

A

paravovirus b19