DNA Viruses Flashcards
all viruses are ___ except for 7 which are ___
all viruses are RNA
except 7 which are DNA
what are the 7 that are DNA viruses
3 are enveloped - hepa, herpes, pox
3 are naked - papilloma, adeno, papova
(need to get naked to get PAP smear)
1 is single stranded - parvo
all DNA viruses are __ stranded
1 exception?
DNA viruses =double stranded
except parvovirus which is single stranded
all DNA viruses are __ in shape
1 exception?
DNA viruses = icosahedral
except “pox” viruses which are complex BRICK shaped
what virus causes cold sores or fever blisters?
what virus causes painful genital ulcers?
herpes simplex virus 1
herpes simplex virus 2
how are herpes simplex viruses 1 and 2 spread?
direct contact
chicken pox is also known as
herpes zoster
or
varicella zoster virus
herpes zoster and chicken pox are also known as what HHV type
herpes virus type 3
how is chicken pox or herpes zoster spread?
aerosol droplets
what is the adult form of chicken pox
shingles
what is human herpes virus type 4?
HHV4
mononucleosis
or
Epstein barr virus
how is mononucleosis spread
kissing
what are symptoms of mononucleosis?
sore throat
fatigue
cervical lymphadenopathy
hepatosplenomegaly
what cells are present in mononucleosis
Downey cells which are atypical lymphocytes
IgM heterophile antibodies
what test is positive in mononucleosis
Paul Bunnel test
what 2 diseases can mononucleosis lead to or cause
burkitts lymphoma
or
nasopharyngeal carcinoma
what is human herpes virus 5
HHV5
cytomegalovirus
what does cytomegalovirus cause in immunocompromized patient? neonates?
interstitial pneumonia in immunocompromized patients
congenital abnormalities, brain calcification, and hepatosplenomegaly in neonates
what disease is caused by human herpes virus 6/7?
HHV6 also called 7 sometimes
Exanthema subitum or Roseola Infantium or 6th Disease
what is known as 6th disease
Exanthema subitum
or
Roseola Infantium
what does exanthema subitum cause
sudden rash after a fever in children
(roseola infantium - kids rash)
febrile seizures in children
what disease is caused by herpes virus 8
kaposi sarcoma
what symptoms does herpes virus 8 or kaposi sarcoma cause
purplish oral or skin lesions in AIDS patients
what is also known as 5th disease
slapped cheek syndrome
or
erythema infectiosum
what virus causes slapped cheek syndrome
parvovrius type b19
what does parvovirus type b19 cause
slapped cheeked syndrome or erythema infectiosum or 5th disease
erythema infectiosum or 5th disease causes what symptoms
red rash on face after fever
slapped cheek syndrome
how is hepatitis B spread
blood or sex
what virus causes hepatitis B
hepatitis B DNA virus
what are the symptoms of hepatitis B
jaundice and tender hepatomegaly
what virus causes viral conjunctivitis
adenovirus
what virus causes pink eye
adenovirus
how is adenovirus spread to develop pink eye or viral conjunctivitis
aerosol droplets
what is pink eye also known as
epidemic viral conjunctivitis
what virus causes smallpox
pox virus - variola virus specifically
how is pox virus spread to develop small pox
aerosol droplets
what are present in the epidermis of small pox patients
guarneri inclusion bodies
when was small pox irradicated
1976
what virus causes human papilloma virus
papova virus
what is HPV spread
direct contact or sex
which types of HPV are associated with genital warts and cervical cancer
HPV 16 and 18
which types of HPV are associated with warts on hands and feet
HPV 1 and 4
what virus causes molluscum contagiosum
pox virus
how does pox virus spread to cause molluscum contagiosum
direct contact
what symptoms does molluscum contagiosum cause
papular lesions with central indentation or umbilication
wartlike papular lesions on face, arms, back, buttocks, and genitals and resolves spontaneously after couple months
STD with papular lesions that ulcerate and mimic herpes
what DNA virus causes pharyngitis
adenovirus
what DNA virus causes meningitis in AIDS patients
CMV
what DNA virus causes JC and BK viruses which cause demyelination and UTI/kidney problems
polyomavirus
papovaviruses are divided into what two groups
papillomavirus
polyomavirus
what does JC virus cause
progressive multifocal leukoencephalopathy
what does BK virus cause
UTI and kidney problems
what is the only hepatitis that is DNA in origin
HepB
which DNA viruses latently infects neurons
herpesvirus
what vaccine is given to prevent HPV
gardasil
what is the acute form of varicella zoster
what is the latent form
chickenpox - acute
shingles - latent
what strain of varicella zoster is used in vaccines to prevent chickenpox and diminish shingles recurrence
Oka strain
what DNA virus is associated with owls eye intranuclear inclusion bodies
cytomegalovirus
appearance due to swelling of infected cells
what causes a heterophile negative mononucleosis
what causes a heterophile positive mononucleosis
CMV
EBV
EBV infects what cells
B lymphocytes
causes proliferation and transformation
how do we diagnose EBV
mononucleosis spot test
how is kaposi sarcoma transmitted
sexual contact
HHV 6/7 infects what cells
T lymphocytes
guarnieri bodies are found in what viruses
whats another name for these bodies
pox virus (small pox specifically)
eosinophilic inclusion bodies
what are the different pox viruses
variola virus - causes small pox
vaccinia virus - cause mild disease - used in small pox vaccine
molluscum contagiosum virus
what virus causes 5th disease
paravovirus b19
what virus causes erythema infectiosum
paravovirus b19
