Viruses Flashcards
virus particles are called
virions
virions are composed of DNA or RNA and are encased by a protein coat called
capsid
what surrounds the capsid protein coat
lipoprotein envelope
or nothing if naked
how do you examine viruses
electron microscope
virions can only replicate where
inside a living cell
obligate intracellular parasites
how are viral capsids classified
helical
icosahedral
complex
what is function of capsids
protect genome
receptors to initiate infection
stimulate antibody production
antigen determinant
what refers to capsid and the viral genome together
nucleocapsid
what is located within the envelope
viral specific glycoproteins
VSG
what is the importance of viral specific glycoproteins VSG
how enveloped viruses initiate infection
what are the steps in a viral infection
attachment - viral attachment proteins attach to receptors on host
penetrate - receptor mediated endocytosis or viropexis
uncoating - capsid separates from genome and duplicates
budding - duplication of genome proteins and accumulation of virus inside cell and then virus leaves by budding out
what are examples of killed vaccines
polio vaccine (salk)
rabies vaccine
influenza vaccine
hepatitis A vaccine
how are killed vaccines made
heat or chemicals kill viruses and then patient given vaccine
what are different way to make vaccine
live virus killed virus virion subunits viral polypeptides viral DNA
live vaccines are ___ viral strains
attentuated