Toxicology Flashcards
1
Q
Muscarinic toxidrome, agents, treatment
A
Muscarinic toxidrome - acetylcholine toxicity/cholinergic
Agents such as organophosphates
DUMBELS or SLUDGE D - diarrhoea U - urination M - miosis B - bronchorrhea and body fasciculations and bradycardia E - emesis L - lacrimation S - salivation
S - salivation L - lacrimation U - urination D - defecation G - GI cramping E - emesis
Treatment is chlonergic antagonist such as atropine and pralidoxime.
2
Q
Serotonergic toxidrome
A
Agitation, autonimic instability auch as tachycardia, neuromuscular acitivity such as clonus. Myoclonus, brief hyperreflexia, higher tones. Diaphoresis.
3
Q
Anticholinergic syndrome
A
Anticholinergic syndrome - mad as a hatter, blind as a bat (mydriasis), red as a beet (flushed skin), hot as a hare (dry skin/anhydrosis), dry as a bone, heart races alone. Treatment with physostigmine.
4
Q
Activated charcoal cannot be used in
A
Needs to be used within 1-2 hours. Cannot be used for acids, alkali, alcohols, ions/metals like iron overdose
