Genetics

Question 1

What is the difference between allelic vs locus heterogeneity?

Answer 1

Allelic is when there is different mutations in one gene leading to the same phenotype e.g cystic fibrosis.

Locus heterogeneity is mutations in different gene or loci leading to same phenotype such as tuberous sclerosis

Question 2

What is zero fecundity?

Answer 2

Those with severe disorders less like or never procreate. The more severe the disease, the more common de novo mutations are.