Haematology - Coagulopathy

Question 1

Diagnostic criteria of antiphospholipid syndrome

Answer 1

Clinical

• venous thrombosis
• arterial thrombosis
• 1 or more unexplained foetal death at >10 weeks
• 1 or more premature birth of <34 weeks related to eclampsia, preeclampsia, placental insufficency
• 3 or more unexplained consecutive abortions <10 weeks.

Lab ( more than 1 present, 12 weeks apart) 
- positive b2 glycoprotein 
- positive lupus anticoagulant 
-postive anticardiolupin
-