toxicities Flashcards

1
Q

B blocker toxicity

A

glucagon

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2
Q

amphetamine toxicity

A

NH4Cl - acidify urine

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3
Q

CN poisoning

A

nitrite + thiosulfate

hydroxocobalamin

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4
Q

salicylates

A

NaHCO3

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5
Q

tPA, streptokinase, urokinase

A

aminocaproic acid

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6
Q

what drugs can cause cutaneous flushing

A

vanco adenosine niacin and calcium blockers

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7
Q

how do you prevent doxorubicin induced dilated cardiomyopathy

A

dexrazoxane

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8
Q

what drugs can cause torsades de pointes

A
class IA, class III
TCAs
antipsychs
antiarrythmics
macrolides
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9
Q

what drugs can cause hyperglycemia

A
tacrolimus
protease inhibitors
niacin
HCTZ
corticosteroids
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10
Q

what drugs can cause hypothyroidism

A

lithium
amiodarone
sulfonamides

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11
Q

what drug can cause acute cholestatic hepatitis

A

erythromycin

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12
Q

what drugs can cause hepatic necrosis

A

halothane
valproic acid
acetaminophen

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13
Q

what drugs can cause hepatitis

A

rifampin
isoniazid
pyrazinamide
statins and fibrates

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14
Q

what drugs can cause pancreatitis

A
didanosine
corticosteroids
alcohol
valproic acid
azathioprine
diuretics
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15
Q

what drugs can cause agranulocytosis

A
ganciclovir
clozapine
carbamazepine
colchicine
methimazole
propylthiouracil
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16
Q

what drugs cause aplastic anemia

A
carbamazepine
methimazole
NSAIDs
benzene
chloramphenicol
propylthiouracil
17
Q

direct coombs positive hemolytic anemia

A

methyldopa

penicillin

18
Q

what drugs can cause hemolysis in G6PD

A
Isoniazid
sulfonamides
dapsone
primaquine
aspirin
ibuprofen
nitrofurantoin
19
Q

what drugs cause megaloblastic anemia

A

phenytoin
methotrexate
sulfa drugs

20
Q

what drugs cause gingival hyperplasia

A

phenytoin
ca2 blockers
cyclosporine

21
Q

what drugs can cause myopathy

A
fibrates and niacin and statins
colchichine
hydroxychloroquine
interferon alpha
pencillamine
glucocorticoids
22
Q

what drugs cause photosensitivity

A
FATS
5FU
amiodarone
tetracyclines
sulfonamides
23
Q

what drugs cause sjs

A

antiepileptics
allopurinol
sulfa drugs
penicillin

24
Q

what drugs cause SLE like syndrome

A
sulfa drugs
hydralazine
isoniazid
procainamide
phenytoin
etanercept
alpha methyldopa
25
Q

what drugs can cause seizures

A

isoniazid - B6 Deficiency
buproprion
imipenem
enflurane

26
Q

what drugs can cause SIADH

A

Carbamazepine
cyclophosphamide
ssris

27
Q

what drugs cause pulm fibrosis

A

bleomycin
amiodarone
busulfan
methotrexate

28
Q

disulfiram like rxn

A
metronidazole
cephalosporins
griseofulvin
procarbazine
first gen sulfonylureas
29
Q

what are the sulfa drugs

A
probenecid
furosemide
acetazolamide
celecoxib
thiazides
sulfonamides
sulfasalzine
sulfonylureas