Renal Flashcards
What drugs cause sulfa allergies
acetazolamide
loop and thiazides
sulfa antibiotics
celecoxib
what are the indications for mannitol use
drug overdose
inc ICP
what are the indications for acetazolamide use
gluacoma urinary alkalinization metabolic alkalosis altitude sickness pseudotumor cerebri
Which diuretics do you use in hypercalcemia?
loop diuretics
What are the s/e of loop diuretics
OH DANG
Ototoxicity
Hypokalemia
Dehydration
allergy - sulfa
Nephritis - interstitial
Gout
If someone has a sulfa allergy what loop diuretic can u give them
ethacrynic acid
name the loop diuretics
F the BET
furosemide
Bumetanide
ethacrynic acid
torsemide
name the thiazides
chlorthalidone
hydrochlorthaizide
indapamide
metolazone
what are the s/e of thiazides
hyperGLUC
G - hyerpglycemia
L - hyperlipidemia
U - hyperuricemia
C - hypercalcemia
When are thiazides specifically contraindicated?
diabetes
What are three ways loops and thiazides cause alkalemia
- volume contraction - inc ATII - inc na/H exchange - inc HCO3 reabsorption
- K+ exits cells, H + enters cells
- low K + - H+ rather than K+ is exchanged for Na+ in cortical collecting tubule
How are ARBs different than ACEIs in MOA
dont block bradykinin release
When are ACEIs contraindicated?
bilateral renal stenosis
hypotension
What are the s/e of ACEIs
cough angioedema teratogen inc creatinine hyperkalemia - HYPER***** hypotension
What is the MOA of aliskiren
blocks renin - blocks conversion of angiotensinogen to angio I
