Psych

Question 1

What drugs are used to treat bipolar

Answer 1

1. lithium
2. valproic acid
3. atypical antipsychs

Question 2

Besides an SSRI, what can be used to treat OCD

Answer 2

clomipramine

Question 3

Venlaxafine an SNRI can be used to treat what?

Answer 3

panic disorder
PTSD
GAD

Question 4

MOA of stimulants? name them

Answer 4

methylphenidate, dextraoamphetamine methamphetamine

inc NE, DA in synaptic cleft

Question 5

What are the high potency antipsychs

what is their main S/e

Answer 5

haloperidol
fluphenazine
trifluoperazine
-neuro s/e - EPS

Question 6

what are the low potency antipsychs? what are their main s/e

Answer 6

CT = low radiation
chlorpromazine - corneal deposits
thiordazine -retinal deposits

messy drugs - antiach, anti alpha1, anti H2 s/e

Question 7

What would you treat EPS with

Answer 7

benztropine

diphenhydramine

Question 8

Describe the four steps of EPS evolution

Answer 8

1. 4 hour dystonia - spasm, stiffness
2. 4 day akathisia - restless
3. 4 wk bradykinesia
4. 4 mo TK -oral facial movements –> irreversible

Question 9

What occurs in NMS?

Answer 9

FEVER
F - FEVER
E- encephalopathy
V - vitals unstable
E - enzymes inc
R - rigidity of muscles

Question 10

How are the atypical antipsychs different from antipsychs?

Answer 10

block 5HT2A - less EPS

also have less anticholinergic s/e

Question 11

What are the s/e of clozapine? what about all the ‘pines?

Answer 11

most metabolic risk
agranulocytosis

-all Pines have metabolic risk

Question 12

‘Dones have highest risk of what

Answer 12

EPS

Question 13

Atypicals and antipsychs all do what

Answer 13

can inc QT interval

Question 14

s/e of lithium?

Answer 14

LMNOP

MOVEMENT - Tremor
Nephrogenic DI
O - hypOthyroidism
P - pregnancy problems - ebstein anomaly

Question 15

What is ebstein anomaly

Answer 15

tricuspid valve is abnormal

Question 16

MOA of buspirone? use?

Answer 16

stimulates 5HT1A

GAD

Question 17

Name the SSRIs

Answer 17

fluoxetine paroxetine sertraline citalopram

Question 18

name the SNRIs

Answer 18

venlafaxine, duloxetine

Question 19

What do you treat serotonin syndrome with

Answer 19

cyproheptadine

Question 20

What is duloxetine also used for

Answer 20

diabetic peripheral neuropathy

Question 21

name the TCAs

Answer 21

“tryptilnes” - ami and nor
“pramis” imipramine, desipramine, clomipramine
doxepin and amoxapine

Question 22

What are the s/e of TCAs

Answer 22

three Cs
cardiotoxicity - treat with NaHCO3
convulsions
coma

Question 23

Name the MAOIs

Answer 23

MAO Takes Pride In Shanghai

Tranylcypromine
phenelzine
isocarboxazid
Selegiline

Question 24

What is the main toxicity of MAOIs?

Answer 24

hypertensive crisis with ingestion of tyramine

also dont take with SSRIS/ TCAS - serotonin syndrome

Question 25

Why should you avoid taking st johns wort with any antidepressants?

Answer 25

risk of serotonin syndrome

Question 26

MOA of buproprion, besides depression what is it used for

Answer 26

inc NE and DA - acts in opposition to alpha 2

also used for smoking cessation

Question 27

When is mirtazapine preferred for use?

Answer 27

depressed pts with insomnia - causes sedation

elderly or anorexic - inc appetitie and weight gain

Question 28

Trazodone can be called _____ why?

Answer 28

trazobone - causes male specific s/e - priapism

Question 29

Which drug blocks alpha 2 - the autoreceptor for NE?

Answer 29

mirtazapine

Question 30

A 17-year-old patient has nocturnal bedwetting. What antidepressant is a treatment option for this patient?

Answer 30

Imipramine, a tricyclic antidepressant

Question 31

How long does it take for SSRIs to start working

Answer 31

4-8 weeks

Question 32

Why is buproprion contraindicated in bullimics?

Answer 32

lowers seizure threshold

desipramine is most likely