Toxic responses of the reproductive system

Question 1

Which of the following cell types secretes anti-Mullerian hormone (AMH)?

a. spermatogonium
b. Leydig cell
c. Sertoli cell
d. primary spermatocyte
e. spermatid

Answer 1

c. Sertoli cell

Question 2

Penile erections are dependent on:

a. The CNS
b. sympathetic nerve stimulation
c. helicine (penile) artery constriction
d. corpora cavernosa smooth muscle relaxation
e. a spina reflex arc

Answer 2

d. corpora cavernosa smooth muscle relaxation

Question 3

The corpus luteum is responsible for the secretion of which of the following hormones during the first part of pregnancy?

a. estradiol and hCG
b. progesterone and estradiol
c. progesterone and hCG
d. FSH and LH
e. FSH and progesterone

Answer 3

b. progesterone and estradiol

Question 4

All of the following statements regarding the hypothalamo-pituitary-gonadal axis are true EXCEPT:

a. FSH increases testosterone production by the Leydig cells
b. FSH and LH are synthesized in the anterior pituitary
c. Estradiol provides negative feedback on the hypothalamus and he anterior pituitary
d. GnRH from the hypothalamus increases FSH and LH release from the anterior pituitary
e. The LH spike during the menstrual cycle is responsible for ovulation

Answer 4

a. FSH increases testosterone production by the Leydig cells

Question 5

Which of the following statements is FALSE regarding gametal DNA repair?

a. DNA repair in spermatogenic cells is dependent on the dose of chemical
b. Spermiogenic cells are less able to repair damage from alkylating agents
c. Female gametes have base excision repair capacity
d. Meiotic maturation of the oocyte decreases its ability to repair DNA damage.
e. Mature oocytes and mature sperm no longer have the ability to repair DNA damage

Answer 5

e. Mature oocytes and mature sperm no longer have the ability to repair DNA damage

Question 6

Reduction division takes place during the transition between which two cell types during spermatogenesis?

a. spermatogonium and primary spermatocyte
b. primary spermatocyte and secondary spermatocyte
c. secondary spermatocyte and spermatid
d. spermatid and spermatozoon
e. spermatozoon and mature sperm

Answer 6

b. primary spermatocyte and secondary spermatocyte

Question 7

Which of the following cell types is properly paired with the substance that it secretes?

a. ovarian granulosa cells- progesterone
b. Leydig cells- ABP
c. ovarian thecal cells- estrogens
d. Sertoli cells- testosterone
e. gonadotroph -LH

Answer 7

e. gonadotroph -LH

Question 8

Which of the following statements regarding male reproductive capacity is FALSE?

a. Klinefelter’s syndrome males are sterile
b. FSH levels are often measured in order to determine male reproductive toxicity of a particular toxin
c. Divalent metal ions , such as An, HG, and Cu, act as androgen receptor antagonists and affect male reproduction
d. The number of sperms produced per day is approximately the same in all males
e. ABP is an important biochemical marker for testicular injury

Answer 8

d. The number of sperms produced per day is approximately the same in all males

Question 9

Reduction of sperm production can be caused by all of the following diseases EXCEPT:

a. hypothyroidism
b. measles
c. Crohn’s disease
d. renal failure
e. mumps

Answer 9

b. measles

Question 10

Of the following, which is the LEAST likely to be affected by estrogen?

a. nervous system
b. musculoskeletal system
c. digestive system
d. cardiovascular system
e. urinary system

Answer 10

d. cardiovascular system