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Epidemiology - MIDTERM 4 > Topic 110 - Diseases of swine caused by Escherichia coli (RED) > Flashcards

Topic 110 - Diseases of swine caused by Escherichia coli (RED) Flashcards

1
Q

Name the diseases caused by E.coli in swine:

A
  1. Coli diarrhoea in newborn piglets
  2. Coli diarrhoea in weaned piglets
  3. Oedema disease
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2
Q

Occurrence of coli diarrhoea in newborn piglets:

A

Worldwide, found on large-scale farms

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3
Q

Causative exotoxin of coli diarrhoea in newborn piglets

A

Enterotoxigenic strain

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4
Q

Age susceptible in case of coli diarrhoea in newborn piglets:

A

0-10 day old piglets

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5
Q

Pathogenesis of coli diarrhoea in newborn piglets:

A
  1. per os infection
  2. replication in the gut (toxin production)
  3. Causing diarrhoea, dehydration
  4. Bacteria is shedding in faeces
    susceptibility is decreasing with age
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6
Q

Clinical signs in case of coli diarrhoea in newborn piglets:

A
  1. NO fever
  2. Depression
  3. Yellow diarrhoea
  4. Dehydration
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7
Q

Post mortem lesions in case of coli diarrhoea in newborn piglets

A
  1. Stomach is filled with clotted milk
  2. Gut is flaccid and there is liqcuid accumulation
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8
Q

How to diagnose coli diarrhoea in newborn piglets

A
  1. Isolation of the agent
  2. Identification of the virluence factors
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9
Q

How to treat coli diarrhoea in newborn piglets

A
  1. Oral AB - Whole litter should be treated
  2. Rehydration
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10
Q

Prevention methods for coli diarrhoea in newborn piglets

A
  1. Hygiene
  2. Eliminate predisposing factors
  3. Vaccination
  4. All-in-all-out method
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11
Q

Occurrence of coli diarrhoea in weaned piglets

A

worldwide

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12
Q

Causative exotoxin of coli diarrhoea in weaned piglets

A

Enterotoxigenic strain

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13
Q

Predisposing factors of coli diarrhoea in weaned piglets

A

Weaning
Changing of feed
Transportation
Viruses: Rota, Corona

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14
Q

Pathogenesis of coli diarrhoea in weaned piglets

A
  1. per os infection
  2. replication in the gut (toxin production)
  3. Causing diarrhoea, dehydration
  4. Bacteria is shedding in faeces
  5. There is an inflammation in the gut
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15
Q

When does the clinical signs of coli diarrhoea in weaned piglets appear?

A

1-2 weeks after waning

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16
Q

Clinical signs in case of coli diarrhoea in weaned piglets:

A
  1. Diarrhoea
  2. Purple colorization of areas on the skin
  3. Resulting in decreased weight gain and an unvene stock
17
Q

Post mortem lesions in case of coli diarrhoea in weaned piglets

A

Gastritis
Enteritis
Enlarged lymph nodes

18
Q

Diagnosing methods for coli diarrhoea in weaned piglets

A

Bacterium isolation

19
Q

Treatment for coli diarrhoea in weaned piglets

A
  1. Decreased feed portion
  2. Increased fibre-content of the feed
  3. AB in drinking water
  4. Rehydration
20
Q

Prevention methods for coli diarrhoea in weaned piglets

A
  1. Decreasing the stress factors
  2. Decreased nutrition and increased fibre content
  3. gradual feed change
  4. Give prebiotics and probiotics
  5. Vaccine ⭢ not very effective
21
Q

Occurrence of oedema disease in swine

A

Sporadic.
Mainly in small farms, but appear in large farms as well

22
Q

Causative exotoxin of oedema disease in swine

A

Verotoxigenic

23
Q

Age most susceptible for oedema disease in swine

A

Mainly 1-2 weeks after weaning in rapidly growing pigs

24
Q

Predisposing factors of oedema disease in swine

A

Weaning
Sudden change in diet
High protein content of the food

25
Q

Pathogenesis of oedema disease in swine

A
  1. Verotoxigenic strain colonise in small intestines, where thye replicate
  2. There is a toxin production
  3. Toxin is absorbed into the blood stream
  4. Damages the endothelial cells of small arteries, causing an increased permeability
  5. It is irreversible
26
Q

Clinical signs of oedema disease in swine

A

There is a sudden onset, some of the animals are found dead without any clinical signs
1. Subcutaneous oedema of eyelids and the front of the face
2. Ataxia
3. Flaccid paralysis
4. Dyspnoea
5. NO fever
6. Diarrhoea
7. Sudden death within 36 hours of the onset of clinical signs

Mortality = 100%

27
Q

Post mortem lesions in case of oedema disease in swine

A
  1. The stomach is filled
  2. Oedema
  3. Perivascular oedema in CNS
28
Q

Diagnostic methods of oedema disease in swine

29
Q

Treatment methods of oedema disease in swine

A

The diseased animals are not feasible to treat, but the littermates are given oral AB and laxants

30
Q

Prevention methods for oedema disease in swine

A
  1. Decreased portion and increased fiber content
  2. Gradual change of the feed
  3. Antibiotics in the feed
  4. Vaccines
31
Q

Type of vaccine used against oedema disease in swine

A

Inactivated toxin
AND
Using fimbriated strains, not toxins

Epidemiology - MIDTERM 4 (31 decks)

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