!!! General mycobacteria !!! Flashcards
What is mycobacteria?
A gram+ bacteria causing tuberculosis
Which type of pathogen is the mycobacterium?
It is:
- Obligate pathogenic
- Facultative pathogenic
- Saprhophytic pathogenic
Where can the obligate pathogenic myocobacterium replicate?
In the infected animal only
Where can the facultative pathogenic myocobacterium replicate?
Can replicate in:
- Infected animals
- Environment
- Plants
- Water
- Gut
Where can the saprophytic pathogenic myocobacterium replicate?
Can replicate in:
- Infected animals
- Environment
- Plants
- Water
- Gut
How the morphology of the mycobacterium?
They are rod shaped, but can also have different shapes: coccoid, filaments.
The contain a cell wall
All the componenets will make a specific factor, what is the name of it and what does it mean?
= Cord factor
The bacteria attach to each other, like a small rope
Name the components of the cell wall of mycobacterium:
- Lipoids ⭢ High amount
- Mycolic acid
- Wax
- Glycolipids
What is typical with the cell wall of the mycobacterium?
It contains components, which makes the mycobacterium extremely resistant, and these components also have a antiphagocytic effect where they inhibit the phagocytosis
How can we stain the mycobacterium?
Ziehl-Neelsen
Incubation time of the mycobacterium:
VERY slow replication
= Several weeks or months
Can there be a cross reaction between the mycobacterias? If yes, what makes this possible?
YES
The glycolipids and lipoproteins in the cell wall as well as the close antigen relationships
What is tuberculin?
A special antigen extract, used for diagnostics
How is the resistance of mycobacterium?
Very good !!
Despite the bacteria being non-spore forming, but due to the cell wall it is good.
How long can mycobacteria survive in different surroundings:
- Sunshine = 12 hours
- Dried discharge = 2-5 months
- Dung = 3 weeks
- Heat = They cannot stand boiling, but they will survive for 20 min in a temperature of 80°C
