Tissues Flashcards
What is a tissue?
A group of cells that usually have a common origin in an embryo and function together to carry out specialized activities.
4 Types of Tissues
Epithelial, connective, muscle, nervous
What are cell junctions?
Contact points between the plasma membranes of tissue cells
Tight junction
fuse together the outer surfaces of adjacent plasma membranes to seal off passageways between adjacent cells
Adherens junction
contains plaque, a dense layer of proteins on the inside of the plasma membrane that attaches both to membrane proteins and to microfilaments of the cytoskeleton.
What is a cadherin?
Transmembrane glycoprotein that join cells by inserting into plaque of adjacent cell
Desmosomes
contain plaque and have transmembrane glycoproteins (cad- herins) that extend into the intercellular space between adjacent cell membranes and attach cells to one another; does NOT attach to microfilaments but intermediate filaments
Hemidesmosomes
resemble desmosomes, but they do not link adjacent cells; anchor cells to the basement membrane
Integrin
transmembrane glycoproteins in hemidesmosomes
Gap Junctions
membrane proteins called connexins form tiny fluid-filled tunnels called connexons that connect neighboring cells
Function of desmosomes
prevent epidermal cells from separating under tension and cardiac muscle cells from pulling apart during contraction.
Function of adherens
Help epithelial surfaces resist separation during various contractile activities
Function of gap junctions
transfer of nutrients and wastes, communication
3 Differences bw Epithelial and Connective tissues
(1) number of cells in relation to ECM (2) epithelial has no blood vessels (3) epithelial almost always surface layer
What is epithelial tissue made of?
cells arranged in continuous sheets, in either single or multiple layers
Functions of epithelium
protects, secretes (mucus, hormones, and enzymes), absorbs (nutrients in the gastrointestinal tract), and excretes (various substances in the urinary tract)
Basal lamina
layer of basement membrane closer to epithelial cell; adhere to integrins in hemidesmosomes
Reticular lamina
layer of basement layer closer to underlying connective tissue; anchors to connective tissue
(T/F) Epithelial tissue has a high rate of cell division
True. It undergoes much mechanical stress so it need it.
2 Types of epithelial tissue
covering and lining and glandular
Simple epithelium
a single layer of cells that functions in diffusion, osmosis, filtration, secretion, or absorption
Pseudostratified epithelium
apical surface may contain cilia; others (goblet cells) secrete mucus.
Stratified epithelium
consists of two or more layers of cells that protect underlying tissues
Squamous cells
thin, which allows for the
rapid passage of substances through them.
Columnar cells
protect underlying tissues. Their apical surfaces may have cilia or microvilli, and they often are specialized for secretion and absorption.
Cuboidal cells
may have microvilli at their apical sur- face and function in either secretion or absorption.
Transitional cells
change shape, from squamous to cuboidal and back, as organs such as the urinary bladder stretch
2 Types of simple squamous epithelium
endothelium- lines heart, blood and lymph vessels
mesothelium- serous membranes
Which cell types have cilia/microvilli?
cuboidal and columnar
Where is covering and lining epithelium located?
Skin, some internal organs, inner lining of blood vessels, ducts, and body cavities, and the interior of the respiratory, digestive, urinary, and reproductive systems.
2 Types of stratified squamous epithelium
keratinized and non-keratinized
Endocrine glands
secrete hormones, no ducts, directly into bloodstream
Exocrine glands
secrete their products into ducts that empty onto the surface of a covering and lining epithelium