Cells Flashcards

1
Q

Cholesterol

A

a steroid with an attached OH (hydroxyl) group

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2
Q

Glycolipid

A

lipids with attached carbohydrate groups.

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3
Q

T/T the head of the lipid bilayer is hydrophobic

A

False

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4
Q

3 Types of membrane proteins

A

integral, transmembrane, peripheral, glycoprotein

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5
Q

Glycocalyx

A

sugary coat formed by carbohydrate portions of glycolipids and glycoproteins in the PM; allows cells to recognize each other

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6
Q

6 Functions of membrane proteins

A

ion channels, carriers, receptor, linkers, enzymes, cell identity markers

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7
Q

What molecules is the PM highly permeable to? Moderately permeable?

A

oxygen, carbon dioxide, steroids
water, urea
the more hydrophobic or lipid-soluble a substance, the greater the membrane’s permeability to that substance

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8
Q

T/F The inner surface of the plasma membrane is more positively charged

A

False

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9
Q

T/F Na+ is more concentrated inside the cell

A

False

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10
Q

5 Factors that influence rate of diffusion

A

steepness of concentration gradient, temperature, mass of diffusing substance, surface area, diffusion distance

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11
Q

Important example of simple diffusion

A

oxygen and carbon dioxide between blood and body cells, and between blood and air within the lungs during breathing

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12
Q

Most abundant ion channel in the PM

A

K+ or Cl-

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13
Q

Transport maximum

A

Once all of the carriers are occupied, the transport maximum is reached, and a further increase in the concentration gradient does not increase the rate of facilitated diffusion

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14
Q

How does glucose enter the body cells?

A

Carrier mediated facilitated diffusion

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15
Q

Aquaporins

A

integral membrane proteins that function as water channels, play a critical role in controlling the water content of cells; responsible for the production of cerebrospinal fluid, aqueous humor, tears, sweat, saliva, and the concentration of urine

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16
Q

Osmotic pressure

A

amount of pressure needed to restore the starting condition; the higher the solute concentration, the higher the solution’s osmotic pressure

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17
Q

Hypotonic soultion

A

lower concentration of solutes than the cytosol; RBCs hemolysis (burst)

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18
Q

Hypertonic

A

higher concentration of solutes than the cytosol; RBCs crenate (shrink)

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19
Q

2 Sources of energy for active transport

A

(1) hydrolysis of adenosine triphosphate (ATP) is the source in primary active transport; (2) energy stored in an ionic concentration gradient is the source in secondary active transport

20
Q

Most abundant primary active transport pump

A

Na+/K+ ATPase

21
Q

Symporters

A

transporter in secondary active transport that move two substances in the same direction

22
Q

Antiporters

A

transporters in secondary active transport that move two substances in opposite directions

23
Q

6 Steps in receptor mediated endocytosis

A

(1) binding (2) vesicle formation (3) uncoating (4) fusion with endosome (5) recycling of receptors to PM (6) degradation in lysosomes

24
Q

2 Types of phagocytes

A

macrophages and nuetrophils

25
Q

Bulk-phase endocytosis

A

the plasma membrane folds inward and forms a vesicle containing a droplet of extracellular fluid

26
Q

Transcytosis

A

vesicles undergo endocytosis on one side of a cell, move across the cell, and then undergo exocytosis on the opposite side

27
Q

What % of the total cell volume is cytosol?

A

55%

28
Q

Microfilaments

A

thinnest, generate movement and provide mechanical support

29
Q

What does the centrosome consist of?

A

pair of centrioles and the pericentriolar matrix

30
Q

Functions of centrosomes

A

microtubule organizer, pericentriolar matrix organizes mitotic spindles

31
Q

Rough ER

A

synthesize glycoproteins and phospholipids

32
Q

Smooth ER

A

synthesizes fatty acids and steroids; inactivates or detoxifies drugs; removes the phosphate group from glucose-6-phosphate; stores and releases calcium ions that trigger contraction in muscle cells

33
Q

Functions of the golgi complex

A

Modifies, sorts, packages, and transports proteins received from the rough ER; makes transfer, secretory and membrane vesicles

34
Q

Difference between autolysis and autophagy

A

autophagy is the digestion of worn-out organelles
and autolysis is the entire cell

35
Q

Function of proteasome

A

destruction of faulty, damaged, or unneeded proteins

36
Q

T/F Mitochondria play role in apoptosis

A

True

37
Q

T/F the nuclear envelope has a lipid bilayer

A

True

38
Q

Proteome

A

all of an organism’s proteins.

39
Q

T/F Introns code for proteins

A

False. Exons do.

40
Q

Interphase

A

DNA replicates and organelles produced; G1, S, and G2 phases

41
Q

2 Events in the mitotic phase

A

nuclear division (mitosis) and a cytoplasmic division (cytokinesis)

42
Q

Prophase

A

chromatin fibers condense and shorten into chromosomes

43
Q

Metaphase

A

microtubules of the mitotic spindle align the centromeres of the chromatid pairs along the metaphase plate

44
Q

Anaphase

A

centromeres split, separating the two members of each chromatid pair and move toward opposite ends of the cell

45
Q

Telophase

A

chromosomes unravel into chromatin and a nuclear envelope forms around them