Tissue Test Flashcards
tissue
collection of specialized cells and extracellular matrix that perform limited, specialized functions
histology
study of tissues
4 main tissue types
-epithelial -connective -muscle -nervous
epithelial
-lines the external surface of all organs -lines interior of all hollow organs -skin surface (epidermis) -makes up all glands

connective
-provide structure and support -provide transport
muscle
provides movement
nervous
-provides flow of information and control through electrical signaling
main functions of epithelium
-protection -absorption -filtration -secretion -sensation
protection (function of epithelium)
protects of all exposed and internal surfaces
control permeability (function of epithelium)
-different in different areas of the body -by absorption and filtration
provide sensation (function of epithelium)
through specialized epithelial cells
secrete and excrete (function of epithelium)
-through specialized gland cells -exocrine and endocrine
epithelial characteristics
-location -orientation -cellular arrangement -avascular -regenerate
location (epithelial characteristic)
-on all free body surfaces -outside of organs -lining cavities, chambers, and hollow membranes
orientation (epithelial characteristic)
-all have an apical part of a membrane -attatched to a basal surface or basement membrane connecting it to the underlying connective tissue
cellular arrangment (epithelial characteristic)
-cells arranged in close proximity and often attached in sheets -little to no matrix
avascular (epithelial characteristic)
no direct connection to the vascular system (rely on adjacent tissue for nutritient)
regenerate (epithelial characteristic)
constantly regenerated due to presence of specialized stem cells
classification of epithelia
-layers -shape
layers (classification of epithelia)
-simple -stratified -pseudostratified -transitional
shape (classification of epithelia)
-squamos -cuboidal -columnar
simple squamos
-diffusion and rapid filtration -secretion in serous membranes
simple cuboidal
-secretion and absorption -ciliated types propel mucus or reproductive cells -covers surface of ovaries

simple columnar
-secretion and regulated slower absorption -ciliated types propel mucus or reproductive cells -lines entire digestive system from stomach through large intestine (forms a mucosa membrane) -goblet cells dispersed throughout

simple transitional
doesn’t exist
stratified squamos
-protection -found where mechanical stress is high

stratified cuboidal/columnar
-protection -rare -found in ducts of very large glands

stratified transitional
-protection -stretches to accomodate disension of urinary structures -only epithelial tissue to have more than 3-4 layers (in a resting state) -specialized squamos

pseudostratified columnar
-all cells on the basement membrane but vary in height (nuclei appear at different heights) -secretion and regulated slower absorption -lines respiratory tree (forming a mucosa) -goblet cells dispersed throughout -apical cilia provide movement of mucus

pseudostratified columnar
-all cells on the basement membrane but vary in height (nuclei appear at different heights) -secretion and regulated slower absorption -lines respiratory tree (forming a mucosa) -goblet cells dispersed throughout -apical cilia provide movement of mucus
types of glandular epithelia
-endocrine -exocrine
endocrine
-secretions released to surrounding tissue and blood -ductless -ex: hormones

exocrine
-secretions released to the surface of the epithelium -many ducts -ex: sweat

functions of connective tissue
-support and protect -transport -energy storage -defense/immunity
characteristics of connective tissue
-vascularity -made of cells, fibers, and extracellular matric
vascularity of connective tissue
-most CT is highly vascular -tendons, ligaments, cartilage are poorly vascular
cells, fiber, extracellular matrix of connective tissue
-extracellular matric = ground substance + fibers -ground substance = water + specialized sticky proteins (act like glue); consistency varies
cells, fiber, extracellular matrix of connective tissue
-extracellular matric = ground substance + fibers -ground substance = water + specialized sticky proteins (act like glue); consistency varies
3 types of fibers in CT
-collagen -elastic -reticular
collagen fiber
-most abundant -strongest

elastic fiber
-stretchy -retain shape

reticular fiber
-tiny, collagen fibers -make up the skeleton of soft organs (liver, spleen, glands)

CT structures
-cell types -fibers -ground substance
cell types of CT
-fibroblasts -macrophages -fat cells -mast cells
types of CT
-bone -cartilage -dense CT -areolar CT -adipose -reticular CT -blood
bone (osseous tissue)
-highly vascular -cells = osteocytes -cells exist in pockets of liquid matrix, lacunae -surrounded by hard dense matrix of collagen fibers and calcium salts
cartilage
-more flexible than bones -avascular -cells = chondrocytes
3 types of cartilage
-hyaline -elastic -fibrocartilage
fiber of hyaline cartilage
collagen
function of hyaline cartilage
-supports/protects -flexibility/movement -growth reduce friction
location of hyaline cartilage
-ribs -ends of bones at articulating joints -larynx/trachea -end of nose
fiber of elastic cartilage
collagen elastic
functions of of elastic cartilage
-maintain shape and flexibility -support
locations of elastic cartilage
-ear -epiglottis -larynx
fiber of fibrocartilage
woven collagen bundles
functions of fibrocartilage
-shock absorbance -provides sturdiness and allows flexibility -deepens sockets
locations of fibrocartilage
-between vertebrae -pelvic bones -ridge of ball-socket joints
locations of fibrocartilage
-between vertebrae -pelvic bones -ridge of ball-socket joints
dense CT (dense fibrous tissue)
-avascular -cells = fibroblasts -matrix = collagen fibers and elastic -fibers aligned parallel to make tendons and ligaments -fibers woven like a carpet or base of skin
loose CT
-fibers are loosely arranged -highly vascular -many cell types
3 types of loose CT
-areolar -adipose -reticular
areolar CT
-most widely distributed -highly vascular -cobweb like appearance -most membranes -holds excess fluid in injury, expands in edema

adipose CT
-fat -cells = adipocytes -main storage of energy -cushions and insulates

reticular CT
-delicate fibers -cell = reticulocytes (tiny fibroblasts) -forms internal framework of some organs and glands

fluid CT
-blood (vascular) -cells = blood cells -matrix = fluid plasma -main function = transport -lymph fluid of lymphatic system circulates immune white blood cells

types of muscle tissue
-skeletal -smooth -cardiac
skeletal muscle tissue
majority of large musclature

smooth muscle tissue
walls of blood vessels and hollow organs

cardiac muscle tissue
heart muscle

muscle tissue
-specialized contractile tissue -produce movement -special actin and myosin filments
neural tissue
-cell types = neuron, neuroglia -conducts electrical impulses, transfers, processes, stores information
neuron cell (neural tissue)
conduct electrical commation
neurolgia (neural tissue)
provide structural support
tissue injury and repair
-injury causes damage to tissue -reponse by all tissues through chemical signaling -response is to restore to homeostasis
nervous tissue
-cell types = neuron, neuroglia -conducts electrical impulses, transfers, processes, stores information -brain, spinal cord, nerves
inflammation
-isolate injured area (swelling) -cleanup damaged tissue (macrophages) -signs of inflammation = warmth, redness, swelling, pain
inflammation
-isolate injured area (swelling) -cleanup damaged tissue (macrophages) -signs of inflammation = warmth, redness, swelling, pain
regeneration
-repair/replace damaged tissue with stem cells -restoration of tissue function -fibrosis = replacement of normal tissue by fibrous connective tissue (scar tissue)
what has good regeneration
-epithelia -most CT -smooth muscle
what has poor regeneration
-cartilage -nerve -other muscle
what has poor regeneration
-cartilage -nerve -other muscle
aging tissue
-repair and maintenance rate decreases -metabolic decline due to lifestyle/hormonal changes -CT becomes more fragile -epithelial tissue thins as the rate of cell death increases and repair/replacement decreases -cancer risk rate increases 25% -most cancers due to environmental factors