thyroid and parathyroid disorders Flashcards
Age-Related Changes in Thyroid Function
Increased incidence of thyroid nodules
Serum levels of T4 remain approximately the same in a healthy older person, but levels of T3 often decline
Incidence of hypothyroidism increases with age, especially among women
Health history
Changes in energy level, sleep patterns, personality, mental function, emotional state
Unexplained weight changes
In the review of systems, changes in menstrual cycles, sexual function, hydration, bowel elimination pattern, and tolerance of heat and cold
Physical examination
Vital signs and height and weight
Facial expression and characteristics as well as mental alertness
Inspect/palpate skin for moisture, temperature, texture
Hair texture
Examine the eyes for exophthalmos (bulging)
Inspect the neck for enlargement typical of goiter. Observe the hands for tremor
Diagnostic tests and procedures
Serum T3, free T4, T4, and TSH Thyroid-releasing hormone (TRH) stimulation test Radioactive iodine (RAI) uptake test Thyroid ultrasonography MRI or CT
Abnormally increased synthesis & secretion of thyroid
hormones
Affects all body systems
Hyperthyroidism
Causes of Hyperthyroidism
Autoimmune disease (Graves’ Disease most common)
Psychological, physiological stress (infection)
Thyroiditis (radiation induced)
Pituitary tumors
Thyroid adenomas
Genetic
Toxic Multinodular Goiter….Note: not all patients with a
goiter have hyperthyroidism
Classic sign of hyperthyroidism
is heat intolerance
hyperthyroidism Can result from
overactivity (Graves’ disease) or a change in thyroid gland (toxic nodular goiter)
Most often develops in young women between 20 & 40, but can occur at any age
Most common type of hyperthyroidism
Autoimmune disorder
Antibodies activate TSH receptors, which in turn stimulate thyroid enlargement and hormone secretion
Graves’ disease
Often in women (4 time more than men) in their 60s and 70s
Likely develop in people who have had goiter for a number of years
Caused by small thyroid nodules that secrete excess thyroid hormone
Increased hormone production is independent of TSH
Nodules can be benign or malignant
Symptoms are usually less severe
Multinodular Goiter
s/s of hyperthyroidsm
Weight loss and nervousness with a mild form
In more severe cases
Restlessness, irritable behavior, anxiety, mood swings, sleep disturbances, personality changes,
Hair loss, and fatigue
Weight loss, even when the patient is eating well, is common; increased hunger
Poor tolerance of heat and excessive perspiration, flushed skin
Changes in menstrual and bowel patterns
Warm, moist, velvety skin; fine hand tremors; swelling of the neck; and ophthalmopathy including exophthalmos (more common with Graves)
Tearing, light sensitivity, decreased visual acuity, and swelling around orbit of the eye
Tachycardia, increased systolic blood pressure, palpitations sometimes atrial fibrillation
Dyspnea, tachypnea
Bruit over thyroid
Diarrhea
Complications hyper
Thyrotoxicosis (aka Thyroid Storm)
Excessive stimulation caused by elevated thyroid hormone levels that produce dangerous tachycardia and hyperthermia
Potential for heart failure
Occurs when hyperthyroidism is untreated or poorly controlled or when the person is severely stressed (trauma, infection, diabetic ketoacidosis, pregnancy).
Do not vigorously palpate a goiter.
Rare with today’s meds, but can occur after surgery
Medical Diagnosis
hyper
Decreased TSH and elevated serum T4
Measurement of thyroid-stimulating antibodies and results of a radioactive iodine uptake test to diagnose Graves’ disease
Thyroid scans
Medical Treatment hyper
Drug therapy
Antithyroid drugs
Thionamides and iodides (blocks production)
Digoxin (for heart failure when it occurs)
Glucocorticoids (reduces immune & inflammatory response)
Iodine prep (decreases blood flow to the through the thyroid gland)
Sedatives (reduce anxiety)
Adrenergic blocking agents (relieves sweating, anxiety, and arrhythmias)
Radioactive iodine
Accumulates in the thyroid gland, where it causes destruction of thyroid tissue
Surgical treatment
Subtotal thyroidectomy
High protein, high carb, high calorie diet restricting stimulants
Care of the Nonsurgical Patient assess. hyper
Activity tolerance
Heat tolerance
Bowel elimination pattern, appetite, weight changes, and food intake
Mental-emotional state, adaptation to the condition, and understanding of the treatment
Measure vital signs and height and weight
Skin texture and edema