pancreas liver gallbladder Flashcards

1
Q

After a meal, excess glucose molecules are taken up by the liver, combined, and then stored as glycogen

A

Glycogenesis (gli-co- genesis)

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2
Q

When blood glucose level falls, the process is reversed, and the glucose molecules are returned to the blood

A

Glycogenolysis (gli-co-geno-lysis)

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3
Q

Fats and protein broken down in response to low blood glucose levels, and molecules are used to make new glucose

A

Gluconeogenesis (glu-co-neo-genesis)

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4
Q

Primary palmar erythema

A

Heredity.
Pregnancy (due to alterations in skin function and vasculature).
Idiopathic.

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5
Q

Secondary palmar erythema

A

Livercirrhosisand its many causes includingalcohol abuse.[(Palmar erythema develops as a result of abnormal oestradiol levels.)
Hereditary liver disease such asWilson’s diseaseandhereditary haemochromatosis.

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6
Q

Locally, inflammatory process causes the liver to swell
Bile channels compressed; damage the cells that produce bile
Then blood flow through the liver is impaired, causing pressure to
rise in the portal circulation
Systemic effects related to altered metabolic functions performed by
the liver and to the infectious response in viral

A

Hepatitis

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7
Q

Signs and symptoms

Hepatitis

A

Signs and symptoms of systemic effects: rash, arthritis, fever,
malaise and angioedema, (the rapid swelling [edema] of
thedermis,subcutaneous tissue,mucosa and submucosal
tissues.)

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8
Q

: caused by exposure to toxic chemicals; drugs

A

Noninfectious: Hepatitis

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9
Q

Exposure to fecal contaminated water, food or
medical equipment. Most common type of viral
hepatitis

A

hep A

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10
Q

Blood borne, found in all body fluids of infected….
Transmit by intimate contact with carriers, exposure to
infected blood

A

hep B

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11
Q

Becomes “C”hronic and a “C” arrier of Hep.

Increases risk of chronic liver infections

A

Hep C

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12
Q

Caused by delta agent… RNA virus that can only
survive in the presence of Hep B..therefore blood
borne

A

hep D

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13
Q

Similar to Hep A.. Trasmit via water or food… rare in

US. No long term effects

A

Hep E

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14
Q

: Identified in some blood donors and transmits by
blood transfusion… does not cause chronic hepatitis..
But effects not fully known

A

Hep G

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15
Q

Signs and symptoms regardless of cause are similar
Preicteric phase
Hepatitis

A

Malaise, severe headache, right upper quadrant abdominal pain, anorexia, nausea, vomiting, fever, arthralgia (joint pain), rash, enlarged lymph nodes, urticaria, liver enlargement and tenderness

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16
Q

Icteric phase

Hepatitis

A

Jaundice, light or clay-colored stools, dark urine

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17
Q

Posticteric phase

Hepatitis

A

Fatigue, malaise, and liver enlargement

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18
Q

Medical diagnosis

Hepatitis

A

Elevated levels of serum enzymes (AST, ALT, GGT), serum and urinary bilirubin, and urinary urobilinogen

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19
Q

Medical treatment

Hepatitis

A

No cure: treat to promote healing and manage symptoms
Antipyretics, corticosteroids, and antiemetics
Diet: high calorie, high carbohydrate, moderate to high protein, and moderate to low fat with supplementary vitamins

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20
Q

Prevention

Hepatitis

A

Vaccines; immune globulin (IG); hepatitis B immune globulin (HBIG)

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21
Q

Nursing Assessment

Hepatitis

A

General health state, drug and alcohol use, chemical exposure, dietary habits, blood transfusions, recent travel, gastrointestinal disturbances, and changes in skin, urine, or stools
Vital signs, skin, weight changes, and mental status

22
Q

Chronic, progressive disease
Degeneration and destruction of liver cells
Fibrotic bands of connective tissue impair the flow of blood and lymph and distort the normal liver structure

23
Q

Incidence

Cirrhosis

A

Fifth leading cause of death in ages 40 to 60 in the United States
More common in men than in women
Related to alcoholic liver disease or chronic viral infection

24
Q

Types

Cirrhosis

A

Alcoholic
Postnecrotic
Biliary
Cardiac (severe and longstanding, hepatic congestion can lead to fibrosis; if congestion is due to right heart failure, it is calledcardiac cirrhosis)

25
s/s | Cirrhosis
Early: slight weight loss, unexplained fever, fatigue, and dull heaviness in the right upper abdomen Progresses: anorexia, nausea, vomiting, diarrhea or constipation, flatulence, dyspepsia, esophageal varices, infections, and epistaxis Later: jaundice; testicular atrophy, impotence, and gynecomastia; ascites; amenorrhea; palmar erythema and spider angiomas; confusion and decreasing consciousness; peripheral neuropathy
26
Complications | Cirrhosis
Portal hypertension, esophageal varices, ascites, hepatic encephalopathy, and hepatorenal syndrome
27
Medical Treatment | Cirrhosis
Bed rest Diet high in carbohydrates and vitamins with moderate to high protein unless blood ammonia level is elevated Intravenous fluids Anemia may require blood transfusions Water and sodium likely to be restricted Cathartics and antibiotics for hepatic encephalopathy
28
Medical diagnosis | Cirrhosis
Liver function tests, CBC, prothrombin time, protein, electrolytes, albumin, bilirubin, urine bilirubin, urobilinogen, liver biopsy, liver scan, ultrasonography, angiography, CT, and MRI Liver biopsy
29
Medical Treatment continued Ascites Cirrhosis
``` Various types of diuretics Salt-poor albumin may be given intravenously Paracentesis Peritoneal-venous shunt of the transjugular intrahepatic portosystemic shunt ```
30
Bleeding esophageal varices Medical Treatment continued Cirrhosis
``` Drug therapy, sclerotherapy (inj. of med), surgical ligation, and placement of an esophageal-gastric balloon tube ```
31
Rarely begins in the liver but frequent site of metastasis Cirrhosis is a predisposing factor As disease progresses, signs and symptoms are essentially the same as those of cirrhosis
Cancer of the Liver
32
Signs/symptoms | Cancer of the Liver
Signs/symptoms: liver enlargement, weight loss, anorexia, nausea, vomiting, dull pain in upper right quadrant of abdomen Because early signs and symptoms of liver cancer are vague, the condition often not diagnosed until advanced
33
test | Cancer of the Liver
Tests: liver scan and biopsy, hepatic arteriography, endoscopy, and measurement of alpha-fetoprotein levels If the cancer is confined to one area, a lobectomy may be done; otherwise chemotherapy is the primary treatment
34
Cholecystitis
Inflammation of the gallbladder Caused by gallstones but can be due to bacteria, toxic chemicals, tumors, anesthesia, starvation, and opioids When gallstones present, called Cholelithiasis. Stones may be found anywhere in the biliary tract: gallbladder, cystic duct, or the common bile duct
35
Signs and symptoms | Cholecystitis and Cholelithiasis
From mild indigestion to severe pain, fever, jaundice Also nausea, eructation, fever, chills, and right upper quadrant pain that radiates to the shoulder If bile flow obstructed, bile production decreases and serum bilirubin rises; leads to obstructive jaundice Some excess bilirubin is excreted in the urine, creating a dark, amber color Digestion of fats is impaired, causing intolerance of fatty foods and steatorrhea
36
Complications | Cholecystitis and Cholelithiasis
Pancreatitis, abscesses, cholangitis, and rupture of the gallbladder
37
Medical diagnosis | Cholecystitis and Cholelithiasis
History and physical examination Fluoroscopy using contrast medium injected directly into the biliary tree Radiographs, radionuclide imaging, ultrasonography, and oral or intravenous cholangiography White blood cell count, serum and urinary bilirubin, and serum enzymes
38
Medical treatment | Cholecystitis and Cholelithiasis
``` Analgesics, anticholinergics, and antibiotics Intravenous fluids Nasogastric tube Drug therapy Shockwave lithotripsy Endoscopic sphincterotomy Cholecystectomy ```
39
Islets of Langerhans
Alpha cells produce and secrete glucagon Beta cells produce and secrete insulin Delta cells produce somatostatin, which inhibits the release of glucagon and insulin Glucagon is secreted when BG level drops and Insulin is secreted when BG rises
40
Pancreatitis
Inflammation of the pancreas May be acute or chronic Caused by biliary tract disorders or alcoholism Also viral infections; peptic ulcer disease; cysts; metabolic disorders; trauma from external injury, surgery, or endoscopy Digestive enzymes activated by unknown mechanism begin to digest pancreatic tissue, fat, and elastic tissue in blood vessels Chronic pancreatitis related to alcohol abuse
41
Signs and symptoms | Pancreatitis
Abdominal pain Severe, with a sudden onset; centered in the upper left quadrant or the epigastric region and radiates to the back Severe vomiting, flushing, cyanosis, and dyspnea often accompany the pain Low-grade fever, tachypnea, tachycardia, hypotension Abdomen may be tender and distended Bowel sounds may be absent Bleeding and shifting of fluid may lead to shock
42
Complications | Pancreatitis
Pseudocyst, abscess, hypocalcemia, and pulmonary, cardiac, and renal complications
43
Medical diagnosis Pancreatitis
Elevated serum amylase, serum lipase, and urinary amylase levels Elevated WBC count, elevated serum lipid and glucose level, and decreased serum calcium level Ultrasonography and ERCP Secretin stimulation test and fecal studies
44
Medical treatment Pancreatitis
Nothing by mouth Nasogastric tube Intravenous fluids Blood or plasma expanders Urine output should be at least 40 mL/hour Jejunal feeding tube or total parenteral nutrition Once food permitted, usually bland, low-fat, high-carbohydrate diet divided into frequent, small meals Prophylactic antibiotics
45
Nursing Assessment | Pancreatitis
Abdomen should be inspected for discoloration, distention, tenderness, and diminished bowel sounds
46
Quickly spreads to the duodenum, stomach, spleen, and left adrenal gland Risk factors: chronic pancreatitis and smoking Also high-fat diet, exposure to toxic chemicals
Cancer of the Pancreas
47
Signs and symptoms | Cancer of the Pancreas
Pain, jaundice with or without liver enlargement, weight loss, and glucose intolerance Other signs and symptoms may be weight loss, upper abdominal pain, anorexia, vomiting, weakness, and diarrhea
48
Medical diagnosis | Cancer of the Pancreas
Transabdominal ultrasound, computed tomography, ERCP, and endoscopic ultrasonography Serum amylase, lipase, bilirubin, and enzyme levels; carcinoembryonic antigen and CA 19-9 titers
49
Assessment | Cancer of the Pancreas
Assess gastrointestinal function, pain, and emotional state | If surgery planned, determine the patient’s knowledge about pre- and postoperative care
50
Cancer of the liver is usually
Secondary
51
Liver usually has pain to the what extremity
Right shoulder