THYROID Flashcards
WHAT IS HASHIMOTOS DISEASE
AUTOIMMUNE CONDITION CAUSING HYPOTHYROIDISM
MYXEDEMA COMA
POTENTIALLY FATAL COMPLICATION OF HYPOTHYROIDISM
TREATMENT IS IV LEVOTHYROXINE
SIGNS AND SYMPTOMS OF HYPOTHYROIDISM
MOM’S SO TIRED
MEMORY LOSS/MENTAL IMPAIRMENT
OBESITY (WEIGHT GAIN)
MENORRHAGIA
SLOWNESS
SKIN/HAIR DRYNESS
ONSET IS GRADUAL
TIRED
INTOLERANCE TO COLD
RAISED BLOOD PRESSURE
ENERGY LEVELS LOW
DEPRESSED
KEY DRUGS THAT CAN CAUSE HYPOTHYROIDISM
I TALC
INTERFERONS
TKIs
AMIODARONE
LITHIUM
CARBAMAZEPINE
HOW OFTEN SHOULD THYROID BE CHECKED
EVERY 4 - 6 WEEKS
HOW TO CALCULATE REPLACEMENT DOSE FOR LEVOTHYROXINE
= 1.6 MCG/KG/DAY
USING IBW
IF THERE IS A KNOWN CAD, WHAT DOSE OF LEVOTHYROXINE SHOULD YOU START WITH
12.5 - 25 MCG DAILY
LEVOTHYROXINE IV:PO RATIO
0.75 : 1
LEVOTHYROXINE TABLET COLORS
ORANGUTANS WILL VOMIT ON YOU RIGHT BEFORE THEY BECOME LARGE PROUD GIANTS
ORANGE, WHITE, VIOLET, OLIVE, YELLOW, ROSE, BROWN, TURQUOISE, BLUE, LILAC, PINK, GREEN
SIGNS AND SYMPTOMS OF HYPERTHYROIDISM
SWEATING
SWEATING
WEIGHT LOSS
EMOTIONAL LABILITY
APPETITE INCREASED
TREMOR/TACHYCARDIA FROM AF
INTOLERANCE TO HEAT/IRRITABILITY
NERVOUSNESS
GOITER/GI PROBLEMS
GRAVES DISEASE
AUTOIMMUNE CONDITION THAT CAUSES HYPERTHYROIDISM
KEY DRUGS THAT CAN CAUSE HYPERTHYROIDISM
IODINE
AMIODARONE
INTERFERONS
WHAT AGENT CAN BE USED FOR SYMPTOM MANAGEMENTS OF HYPERTHYROIDISM
BETA BLOCKERS
WHAT MEDICATIONS LOWER THYROID LEVELS IN HYPERTHYROIDISM
PROPYLTHIOURACIL
METHIMAZOLE
HOW ARE ANTITHYROID MEDICATIONS TYPICALLY USED
THEY ARE USED AT HIGH DOSES TO CONTROL SYMPTOMS FOR 1 - 3 MONTHS
THEN DOSE SHOULD BE REDUCED TO PREVENT HYPOTHYROIDISM
BOXED WARNING FOR PTU
SEVERE LIVER INJURY AND ACUTE LIVER FAILURE
WHICH THIONAMIDE IS PREFERRED IN PREGNANCY
PTU FOR 1ST TRIMESTER
METHIMAZOLE CAN BE USED DURING 2ND AND 3RD
THIONAMIDES WARNING
HEPATOTOXICITY
AGRANULOCYTOSIS
DRUG INDUCED LUPUS
WHICH THIONAMIDE IS GENERALLY PREFERRED
METHIMAZOLE
LOWER RISK OF LIVER DAMAGE
WHICH THIONAMIDE IS PREFERRED IN THYROID STORM
PTU
WHAT IS THE MECHANISM OF IODIDES USE IN HYPERTHYROIDISM
TEMPORARILY INHIBIT SECRETIONS OF THYROID HORMONES
WHY IS POTASSIUM IODIDE USED AFTER RADIATION
BLOCKS THE ACCUMULATION OF RADIOACTIVE IODIDE, PREVENTING THYROID CANCER
WHAT IS THYROID STORM
LIFE THREATENING
DECOMPENSATED HYPERTHYROIDISM
SIGN AND SYMPTOMS OF THYROID STORM
FEVER
TACHYCARDIA/TACHYPNEA
DEHYDRATION
PROFUSE SWEATING
AGITATION
DELIRIUM
PSYCHOSIS
COMA
WHAT IS THE DRUG TREATMENT FOR THYROID STORM
PTU + LUGOL’S + PROPRANOLOL + DEXAMETHASONE
AND AGGRESSIVE COOLING
LEVOTHYROXINE USE IN PREGNANCY. DOSE CHANGES?
SAFE
REQUIRE A 30 - 50 % INCREASE IN DOSE
