THYROID

Question 1

WHAT IS HASHIMOTOS DISEASE

Answer 1

AUTOIMMUNE CONDITION CAUSING HYPOTHYROIDISM

Question 2

MYXEDEMA COMA

Answer 2

POTENTIALLY FATAL COMPLICATION OF HYPOTHYROIDISM
TREATMENT IS IV LEVOTHYROXINE

Question 3

SIGNS AND SYMPTOMS OF HYPOTHYROIDISM

Answer 3

MOM’S SO TIRED
MEMORY LOSS/MENTAL IMPAIRMENT
OBESITY (WEIGHT GAIN)
MENORRHAGIA
SLOWNESS
SKIN/HAIR DRYNESS
ONSET IS GRADUAL
TIRED
INTOLERANCE TO COLD
RAISED BLOOD PRESSURE
ENERGY LEVELS LOW
DEPRESSED

Question 4

KEY DRUGS THAT CAN CAUSE HYPOTHYROIDISM

Answer 4

I TALC
INTERFERONS
TKIs
AMIODARONE
LITHIUM
CARBAMAZEPINE

Question 5

HOW OFTEN SHOULD THYROID BE CHECKED

Answer 5

EVERY 4 - 6 WEEKS

Question 6

HOW TO CALCULATE REPLACEMENT DOSE FOR LEVOTHYROXINE

Answer 6

= 1.6 MCG/KG/DAY
USING IBW

Question 7

IF THERE IS A KNOWN CAD, WHAT DOSE OF LEVOTHYROXINE SHOULD YOU START WITH

Answer 7

12.5 - 25 MCG DAILY

Question 8

LEVOTHYROXINE IV:PO RATIO

Answer 8

0.75 : 1

Question 9

LEVOTHYROXINE TABLET COLORS

Answer 9

ORANGUTANS WILL VOMIT ON YOU RIGHT BEFORE THEY BECOME LARGE PROUD GIANTS
ORANGE, WHITE, VIOLET, OLIVE, YELLOW, ROSE, BROWN, TURQUOISE, BLUE, LILAC, PINK, GREEN

Question 10

SIGNS AND SYMPTOMS OF HYPERTHYROIDISM

Answer 10

SWEATING
SWEATING
WEIGHT LOSS
EMOTIONAL LABILITY
APPETITE INCREASED
TREMOR/TACHYCARDIA FROM AF
INTOLERANCE TO HEAT/IRRITABILITY
NERVOUSNESS
GOITER/GI PROBLEMS

Question 11

GRAVES DISEASE

Answer 11

AUTOIMMUNE CONDITION THAT CAUSES HYPERTHYROIDISM

Question 12

KEY DRUGS THAT CAN CAUSE HYPERTHYROIDISM

Answer 12

IODINE
AMIODARONE
INTERFERONS

Question 13

WHAT AGENT CAN BE USED FOR SYMPTOM MANAGEMENTS OF HYPERTHYROIDISM

Answer 13

BETA BLOCKERS

Question 14

WHAT MEDICATIONS LOWER THYROID LEVELS IN HYPERTHYROIDISM

Answer 14

PROPYLTHIOURACIL
METHIMAZOLE

Question 15

HOW ARE ANTITHYROID MEDICATIONS TYPICALLY USED

Answer 15

THEY ARE USED AT HIGH DOSES TO CONTROL SYMPTOMS FOR 1 - 3 MONTHS
THEN DOSE SHOULD BE REDUCED TO PREVENT HYPOTHYROIDISM

Question 16

BOXED WARNING FOR PTU

Answer 16

SEVERE LIVER INJURY AND ACUTE LIVER FAILURE

Question 17

WHICH THIONAMIDE IS PREFERRED IN PREGNANCY

Answer 17

PTU FOR 1ST TRIMESTER
METHIMAZOLE CAN BE USED DURING 2ND AND 3RD

Question 18

THIONAMIDES WARNING

Answer 18

HEPATOTOXICITY
AGRANULOCYTOSIS
DRUG INDUCED LUPUS

Question 19

WHICH THIONAMIDE IS GENERALLY PREFERRED

Answer 19

METHIMAZOLE
LOWER RISK OF LIVER DAMAGE

Question 20

WHICH THIONAMIDE IS PREFERRED IN THYROID STORM

Answer 20

PTU

Question 21

WHAT IS THE MECHANISM OF IODIDES USE IN HYPERTHYROIDISM

Answer 21

TEMPORARILY INHIBIT SECRETIONS OF THYROID HORMONES

Question 22

WHY IS POTASSIUM IODIDE USED AFTER RADIATION

Answer 22

BLOCKS THE ACCUMULATION OF RADIOACTIVE IODIDE, PREVENTING THYROID CANCER

Question 23

WHAT IS THYROID STORM

Answer 23

LIFE THREATENING
DECOMPENSATED HYPERTHYROIDISM

Question 24

SIGN AND SYMPTOMS OF THYROID STORM

Answer 24

FEVER
TACHYCARDIA/TACHYPNEA
DEHYDRATION
PROFUSE SWEATING
AGITATION
DELIRIUM
PSYCHOSIS
COMA

Question 25

WHAT IS THE DRUG TREATMENT FOR THYROID STORM

Answer 25

PTU + LUGOL’S + PROPRANOLOL + DEXAMETHASONE
AND AGGRESSIVE COOLING

Question 26

LEVOTHYROXINE USE IN PREGNANCY. DOSE CHANGES?

Answer 26

SAFE
REQUIRE A 30 - 50 % INCREASE IN DOSE