OSTEOPOROSIS Flashcards
T SCORE INTERPRETATION
NORMAL ≥ -1
OSTEOPENIA -1 TO -2.4
OSTEOPOROSIS ≤ -2.5
RECOMMENDED CALCIUM INTAKE FOR MOST ADULTS
1000 - 1200 MG ELEMENTAL CALCIUM
WHAT IS CONSIDERED VIT D DEFICIENCY
< 30 NG/ML
WHAT IS THE VIT D DOSING FOR DEFICIENCY
DAILY: 125 - 175 MCG (5000 - 7000 IU)
WEEKLY: 1250 MCG (50,000 IU)
HOW MUCH ELEMENTAL CALCIUM IN CALCIUM CARBONATE
40%
HOW MUCH ELEMENTAL CALCIUM IN CALCIUM CITRATE
21%
CRITERIA FOR INITIATING TREATMENT FOR OSTEOPOROSIS
T SCORE ≤ -2.5 IN SPINE, NECK, HIP OR 1/3 RADIUS
OR
PRESENCE OF FRIGILITY FRACTURES, REGARDLESS OF BMD
CIRTERIA FOR INITIATING TREATMENT IN OSTEOPENIA HIGH RISK
LOW BONE DENSITY (T-SCORE BETWEEN -1 AND -2.5)
AND
FRAX SCORE ANY FRACTURE ≥ 20% OR HIP FRACTURE ≥3%
TERIPARATIDE (FORTEO)
ABALOPARATIDE (TYMLOS)
INDICATION
RECOMMENDED FOR VERY HIGH RISK PTS ONLY
RALOXIFENE (EVISTA)
BAZEDOXIFENE/ESTROGEN (DUAVEE)
INDICATION
ALTERNATIVE TO BISPHOSPHONATES IF HIGH RISK OF VERTEBRAL FRACTURE
WHICH BISPHOSPHONATES ARE INJECTABLE
IBANDRONATE (BONIVA)
ZALEDRONIC ACID (RECLAST)
INDICATION FOR IBANDRONATE
OSTEOPOROSIS TREATMENT IN POSTMENOPAUSAL FEMALES
ZALEDRONIC ACID INDICATIONS
- PREVENTION (POST MENO FEMALE)
- TREATMENT (MALES AND POST MENO FEMALE)
- GLUCOCOTICOID INDUCED OSTEOPOROSIS
ALENDRONATE DOSING OPTIONS FOR PREVENTION
DAILY OR WEEKLY
ALENDRONATE DOSING OPTIONS FOR TREATMENT
DAILY OR WEEKLY
RISEDRONATE DOSING FOR FEMALE
DAILY
WEEKLY
MONTHLY
WHO CAN TAKE DUAVEE
CONJUGATED ESTROGENS/BAZEDOXIFENE
POSTMENOPAUSAL FEMALES WITH A UTERUS
WHO CAN TAKE CALCITONIN FOR OSTEOPOROSIS
FEMALES >5 YEARS POSTMENOPAUSAL
DUAVEE WARNINGS
ENDOMETRIAL CANCER
RISK OF CLOTS
BREAST AND OVARIAN CANCER
PARATHYROID HORMONE 1-34 BOXED WARNINGS
BONE CANCER
RANKL INHIBITORS DOSING FREQUENCY
EVERY 6 MONTHS
RANKL INHIBITOR CONTRAINDICATIONS AND WARNINGS
CI: HYPOCALCEMIA, PREGNANT
WARNING: ONJ, FEMURE FRACTURE
HTN EDEMA, FATIGUE, DYSPEPSIA, HA, N/V/D, LOW PO4
RANKL INHIBITOR CONTRAINDICATIONS AND WARNINGS
CI: HYPOCALCEMIA, PREGNANT
WARNING: ONJ, FEMURE FRACTURE
HTN EDEMA, FATIGUE, DYSPEPSIA, HA, N/V/D, LOW PO4
NATURAL PRODUCTS USED FOR VASOMOTOR SYMPTOMS
BLACK COHOSH
EVENING PRIMROSE
RED CLOVER
SOY
