thyroid

Question 1

triiodothyronine

Answer 1

t3

Question 2

thyroxine

Answer 2

t4

Question 3

Pneumonic for drugs that can cause hypothyroidism

Answer 3

I TALC

Interferons
Tyrosine kinase Inhibitors
Amiodarone
Lithium
Carbamazepime

Conditions: Hashimoto’s

Question 4

How often should TSH be monitored

Answer 4

every 4-6 weeks

Question 5

what can too high of a thyroid dose in elderly cause

Answer 5

afib and fractures

Question 6

synthroid

Answer 6

levothyroxine (t4)

Question 7

levoxyl

Answer 7

levothyroxine (t4)

Question 8

Unithroid

Answer 8

levothyroxine (t4)

Question 9

Cytomel

Answer 9

Liothyronine (T3)

Question 10

Armor

Answer 10

Dessicated thyroid (T3, T4)

Question 11

Levothyroxine Tablet color pneumonic

Answer 11

Orangutans - Orange 25mcg
Will - White 50mcg
Vomit - violet - 75
On - olive - 88
You - Yellow - 100 mcg
Right - Rose 112mcg
Before - Brown 125
They - Turqoise 137 mcg
Become - Blue 150mcg 
Large - 175mcg lilac
Proud - 200mcg Pink
Giants - 300mcg Green

Question 12

Levothyroxine administration

Answer 12

Should be taken with water at least 60 minutes before breakfast or at bedtime 3 hours before last meal

Question 13

When to decrease dose of thyroid meds

Answer 13

in cardiovascular disease or decreased bone mineral density

Question 14

How is levothyroxine dosed

Answer 14

1.6 mcg/kg/day using IBW

Question 15

What drugs decrease levothyronine absorption

Answer 15

Antacids, iron, calcium, aluminum, magnesium, multivitamins, cholestriamine, sevelamer, sucralfate

Question 16

TSH and free T4 labs

Answer 16

want low free T4 (the active form of thyroid hormone) and High TSH

Question 17

IV to PO ratio of IV

Answer 17

0.75 to 1

Question 18

which thyroid replacement drug has short half life

Answer 18

Liothyronine/T3

Question 19

Most common cause of hyperthyroidism

Answer 19

graves disease where antiboidies stimulate thyroid to produce too much T4

Question 20

Drug induced causes of hyperthyroidism

Answer 20

iodine, amiodarone, interferons

Question 21

hypothyroidism in pregnancy tx

Answer 21

use levo but increase dose by 30-50% due to increased metabolism

Question 22

drug tx for thyroid storm

Answer 22

antithyroid therapy (PTU preferred) plus inorganic iodide therapy (SSKI or Lugol’s) plus beta blocker plus steroid systemic plus agressive cooling

Question 23

MOA of thionamides

Answer 23

inhibit the synthesis of thyroid hormones (PTU additionally inhibits peripheral conversion of T4 to T3)

Question 24

Propylthiuracil

Answer 24

PCU

Question 25

What is the drug of choice for hyperthyroidism

Answer 25

Methimazole

Question 26

What is the drug of choice for pregnancy 1st trimester and for thyroid storm

Answer 26

PTU

Question 27

What are the boxed warnings for PTU

Answer 27

Severe liver injury and acute liver failure (may cause DILE and agranulocytosis)

Question 28

how long does it take to control hyperthyroid with medications before dose needs to be reduced

Answer 28

1-3 months

Question 29

What is preffered tx in graves

Answer 29

radioactive iodine or surgery

Question 30

What do iodides do?

Answer 30

temporarily inhiit secretion of thyroid hormones

Question 31

what is potasium iodide for

Answer 31

to block the accumulation of radioactive iodine in thyroid storm

Question 32

general idea of hypothyroidism sx

Answer 32

fatigue, weak, hair loss, mental god, muscle cramps and myalgias, lazy and fat, excessive period because not breaking down estrogen building up

“cooling down system and slowing down”

Question 33

general idea of hyperthyrpoidism

Answer 33

agitated, tremor, no period, agitated and nervous, paliptations and tachy

“heating up”

Question 34

general idea of thyroid storm

Answer 34

life threatening due to decompensated hyperthyroidism and can result in fever, delerium , coma, sweating

Question 35

main cause of hypothyroidism

Answer 35

hashimotos, destroys thyroid gland

Question 36

decompensation of hypothyroidism

Answer 36

myxendema