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My own Naplex > Acute Coronary Syndromes > Flashcards

Acute Coronary Syndromes Flashcards

1
Q

Drug Treatment for ACS

A

MONA-GAP-BA

+/- PCI depending on EKG

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2
Q

abciximab, eptifivatide, and tirofiban are what

A

gp2b/3a antagonists

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3
Q

clopodogrel, prasugrel, and ticagrelor are what

A

p2y12 inhibitors

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4
Q

which two medications should be avoided acutely

A

nsaids and IR nigedipine

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5
Q

clopidogrel and prasugrel classification and binding to receptor

A

thienopyridines that irreversibly bind to receptor

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6
Q

clopidogrel metabolism

A

cyp2c19 prodrug; avoid omeprazole and esomeprazole

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7
Q

prasugrel contraindication

A

do not use in patient with hx of stroke/tia due to bleeding risk.

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8
Q

max asa maint dose on ticagrelor

A

<100mg

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9
Q

ticagrelor dosing

A

90mg bid x 1 year, then 60mg bid

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10
Q

plavix

A

clopidogrel

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11
Q

when to stop prasugrel and ticagrelor

A

prasugrel: 7 days prior to elective surgery
ticagrelor: stop 5 days before any surgery

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12
Q

effient

A

prasugrel

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13
Q

brilinta

A

ticagrelor

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14
Q

cangrelor administration

A

via injection, must transition to an oral P2Y12 after PCI

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15
Q

prasugrel dispensing

A

must be dispensed in original container

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16
Q

all p2y12 inhibitors have what warning besides bleeding

A

TTP

17
Q

reopro

A

abciximab

18
Q

integrilin

A

eptifibatide

19
Q

activase

A

alteplase

20
Q

alteplase moa

A

tissue plasminogen activator (tPA)

21
Q

TNKase

A

tenecteplase

22
Q

fibrinolutic contraindications

A

active internal bleeding, history of recent stroke, severe uncontrolled hypertension

23
Q

clopidogrel dosing

A

75 mg po daily

24
Q

ticagrelor dosing

A

90mg po bid for 1 year, then 60mg bid

25
Q

main side effect/ contraindication of glycoprotein receptor antagonists

A

thrombocytopenia

26
Q

When are fibrinolytics used?

A

STEMI only

27
Q

fibrinolytic moa

A

convert plasminogen to plasmin

28
Q

When should a PCI be done?

A

Preferred: 90 minutes

Max: Within 120 minutes (2 hours)

Optimal: 30 minutes

29
Q

Which is the only fibrinolytic that can be used for acute stroke?

A

Alteplase (different dosing)

30
Q

how long to use asa after MI

A

indefinetly

31
Q

how long to use a p2y12

A

at least 12 months (along with asa)

32
Q

how long to use niroglycerin

A

indefinitely as needed

33
Q

how long to use bb

A

at least 3 years

34
Q

how long to use ace

A

indefinetly if ef < 40, HTN, CKD or diabetes

35
Q

how long to use aldosterone antagonist

A

indefinetly especially if reduced EF but contraindicated in significant renal impairment

36
Q

how long to use statin for

A

indefinetly, high intensity because this counts as a primary prevention event

My own Naplex (39 decks)

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