Drug Use in Pregnancy And Lactation

Question 1

how much folic acid (folate aka B9) should any woman of childbearing age get?

Answer 1

400mcg per day…600?

Question 2

How much calcium should someone who is pregnant get?

Answer 2

1000 mg/day

protecting mom

Question 3

How much vitamin D should someone who is pregnant get?

Answer 3

600 IU

helps ca absorb

Question 4

Pregnancy Catagory A

Answer 4

no risk

Question 5

Pregnancy Category B

Answer 5

animal studies show no risk

Question 6

Pregnancy Category C

Answer 6

animal studies show risk

Question 7

Pregnancy category D

Answer 7

Possible evidence of harm to fetus but benefit outweighs risk

Question 8

Pregnancy Category X

Answer 8

No bueno

Question 9

pregnancy vaccines

Answer 9

no live vacccines, fl shot, Tdap with each pregnancy

Question 10

USP chapter 800

Answer 10

hazerdous drugs

Question 11

resource for pregnancy drugs

Answer 11

briggs drugs in pregnancy and lactation

Question 12

acne teratigenic drugs

Answer 12

isotretinoin, retinoids

Question 13

teratogenic antibiotics

Answer 13

quinalones, tetracuclines

Question 14

teratinogenic anticoagulants

Answer 14

wargarin

Question 15

teratinogenic heart drugs

Answer 15

statins, ace/arb,

Question 16

teratinogenic hormones

Answer 16

contraceptices (i.e. estradiol, progesterone), testosterone

Question 17

teratinogenic migraine meds

Answer 17

dihydroergotamine, ergotamine

Question 18

other important teratinogens

Answer 18

hydroxyuria, lithium, misoprostol, methotrexate, nsaids, paroxetine, ribavirin, topiramate, weight loss drugs, valproic acid

Question 19

what prevents preeclamsia

Answer 19

elevated blood pressure - daily low dose aspirin at the end of the 1st trimester for women with type 1 or 2 diabetes

Question 20

what vitamin should babies reciving breastmilk recieve

Answer 20

400IU vit D daily, 1 mg/kg iron during months 4-6

Question 21

drugs that should be avoided in lactation

Answer 21

amphetamines, amiodarone, erogts, lithium, metronidazome, sttins, phenobarbial

Question 22

what pain med should not be used in pregnancy and whY?

Answer 22

codiene and tramadol because of the the risk of an ultrarapid cyp4502d6

acetaminophen preferred

Question 23

nausea in preg

Answer 23

1) lifestyle
2) pyroxidine (B6 +/- doxalimine (unisom, a sedating antihistamine)

possibly ginger

Question 24

GERD

Answer 24

lifestyle, then tums (also has ca)

Question 25

flatulance

Answer 25

lifestile, then fiber (psilium, calcium polycarbophil)

Question 26

cough

Answer 26

1) cromylyn
2) 1st getn antihistamines (chlorpheniramine doc)

if nasal steroids indicated budosenide and betamethasone preferred

if cough supressant used avoid alch

Question 27

diabetes

Answer 27

insulin (consider aspirin as well for preclampsia)

Question 28

Antibiotics that are considered safe in pregnancy

Answer 28

most b lactams,erythromyucin and azithromycin (macrolides)

Question 29

antibiotics to avoid in pregnancy

Answer 29

quinalones, tetracyclines (teeth)

Question 30

antibiotic for UTI during pregnancy

Answer 30

not bactrim and nitrofurantoin

cephalexin and ampicillin ok

*must treat bacteruria

Question 31

test for toxoplasmosis

Answer 31

igg

Question 32

anticoagulation

Answer 32

lmwh over ufh, warfarin only if mechanical heart valves and at high risk for thromboembolism

Question 33

hypothyroidism

Answer 33

increase levo dose by 30-50%

Question 34

hyperthyroidism

Answer 34

PTU 1st semester then switch to methmiazome for remainder of pregnancy due to less liver damage