Drug Use in Pregnancy And Lactation Flashcards

1
Q

how much folic acid (folate aka B9) should any woman of childbearing age get?

A

400mcg per day…600?

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2
Q

How much calcium should someone who is pregnant get?

A

1000 mg/day

protecting mom

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3
Q

How much vitamin D should someone who is pregnant get?

A

600 IU

helps ca absorb

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4
Q

Pregnancy Catagory A

A

no risk

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5
Q

Pregnancy Category B

A

animal studies show no risk

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6
Q

Pregnancy Category C

A

animal studies show risk

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7
Q

Pregnancy category D

A

Possible evidence of harm to fetus but benefit outweighs risk

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8
Q

Pregnancy Category X

A

No bueno

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9
Q

pregnancy vaccines

A

no live vacccines, fl shot, Tdap with each pregnancy

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10
Q

USP chapter 800

A

hazerdous drugs

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11
Q

resource for pregnancy drugs

A

briggs drugs in pregnancy and lactation

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12
Q

acne teratigenic drugs

A

isotretinoin, retinoids

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13
Q

teratogenic antibiotics

A

quinalones, tetracuclines

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14
Q

teratinogenic anticoagulants

A

wargarin

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15
Q

teratinogenic heart drugs

A

statins, ace/arb,

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16
Q

teratinogenic hormones

A

contraceptices (i.e. estradiol, progesterone), testosterone

17
Q

teratinogenic migraine meds

A

dihydroergotamine, ergotamine

18
Q

other important teratinogens

A

hydroxyuria, lithium, misoprostol, methotrexate, nsaids, paroxetine, ribavirin, topiramate, weight loss drugs, valproic acid

19
Q

what prevents preeclamsia

A

elevated blood pressure - daily low dose aspirin at the end of the 1st trimester for women with type 1 or 2 diabetes

20
Q

what vitamin should babies reciving breastmilk recieve

A

400IU vit D daily, 1 mg/kg iron during months 4-6

21
Q

drugs that should be avoided in lactation

A

amphetamines, amiodarone, erogts, lithium, metronidazome, sttins, phenobarbial

22
Q

what pain med should not be used in pregnancy and whY?

A

codiene and tramadol because of the the risk of an ultrarapid cyp4502d6

acetaminophen preferred

23
Q

nausea in preg

A

1) lifestyle
2) pyroxidine (B6 +/- doxalimine (unisom, a sedating antihistamine)

possibly ginger

24
Q

GERD

A

lifestyle, then tums (also has ca)

25
flatulance
lifestile, then fiber (psilium, calcium polycarbophil)
26
cough
1) cromylyn 2) 1st getn antihistamines (chlorpheniramine doc) if nasal steroids indicated budosenide and betamethasone preferred if cough supressant used avoid alch
27
diabetes
insulin (consider aspirin as well for preclampsia)
28
Antibiotics that are considered safe in pregnancy
most b lactams,erythromyucin and azithromycin (macrolides)
29
antibiotics to avoid in pregnancy
quinalones, tetracyclines (teeth)
30
antibiotic for UTI during pregnancy
not bactrim and nitrofurantoin cephalexin and ampicillin ok *must treat bacteruria
31
test for toxoplasmosis
igg
32
anticoagulation
lmwh over ufh, warfarin only if mechanical heart valves and at high risk for thromboembolism
33
hypothyroidism
increase levo dose by 30-50%
34
hyperthyroidism
PTU 1st semester then switch to methmiazome for remainder of pregnancy due to less liver damage