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My own Naplex > Asthma > Flashcards

Asthma Flashcards

1
Q

Intermittant asthma signs and tx

A

less than 2 days per week and can treat intermittently with ICS + LABA/SABA

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2
Q

Mild asthma signs and tx

A

greater than 2 days per week but not daily. want to tx daily with ICS

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3
Q

moderate asthma

A

daily exacerbations, would do daily low dose ICS/LABA

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4
Q

severe asthma

A

increase ics dose until controlled, still ICS + LABA daily

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5
Q

proair/ventolin

A

albuterol, a SABA

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6
Q

salmeterol

A

LABA

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7
Q

QVAR

A

betamethasone, ICS

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8
Q

Pulmicort

A

Budosenide, ICS

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9
Q

symbicort

A

bucosenids (ICS) + formetalol (LABA)

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10
Q

advair

A

fluticasone (ICS) + salmetarol (LABA)

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11
Q

breo

A

fluticasone (ICS) + vilanterol (LABA)

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12
Q

dulera

A

mometasone (ICS) + formoterol (LABA)

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13
Q

ICS s/e

A

thrush, dysphonia, cough

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14
Q

saba s/e

A

nervousness, tremor, tachycardia, palpitations, cough, hyperglycemia, decreased potassium

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15
Q

laba boxed warning

A

increased risk of asthma related deaths if used alone

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16
Q

spiriva

A

tiotropium (LAMA)

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17
Q

flovent

A

fluticasone (1/2), ICS

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18
Q

Arnuity

A

fluticasone (2/2), ICS

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19
Q

Which ICS/LABA can be used for rescue due to its shorter onset of action

A

symbicort (budosenide + formeterol) and dulera (mometasone + formetorol)

**formetarol

20
Q

What kind of inhaler is DPI?

A

diskus, ellipta, pressair, handihaler, flexhaler, neohaler, respiclock

21
Q

HFA and Respomat is what kind of inheper

A

MDI

22
Q

singulair

A

monteleukast

23
Q

zileuton moa

A

inhibits leukotriene formation

24
Q

boxed warning montelukast

A

a leukotriene modifying agent, boxed warning neuropsychiatric effects

25
Q

monteleukast granual administration

A

can be administered directly in the mouth or dissolved in a small amount of breast milk or formula or mixed with applesauce, carrots, rice, or ice cream. use within 15 min of opening.

26
Q

theophyline dosing weight

A

IBW

27
Q

converting between aminophyline to theophyline

A

ATM -> multiply by .8 and vice versa

28
Q

theophyline theraputic range

A

5-15 mcg/mL

29
Q

theophyline moa

A

blocks PDE resulting in an increase in cAMP and bronchodilation

30
Q

kinetics of theophyline

A

small increase in dose may result in massive increase in concentration and is metabolized (a substrate of) by CYP1A2 and Cyp3A4, also affected by CHF/liver dz and high protein diet/low carb

31
Q

theophyline tox

A

vomiting, arrhythmias, seizures

32
Q

xolair

A

omalizumab

33
Q

what drug is indicatd for allergic asthma in patients with a positive skin test

A

xolair/omalizumab which is a monocolonial antibody that inhibits IgE binding

34
Q

boxed warning for omalizumab

A

anaphylaxis

35
Q

which ics is preferred in pregnancy

A

budosenide (pulmicort)

36
Q

how to administer xolair

A

omilizuman, sQ in a healthcare setting under supervision due to risk of anaphalaxzis

37
Q

dupillusumab, mepolizumab, resilizumab, and benralizumab

A

il receptor antagonsts indicated for eisinophillic phenotype (all il5 except dupilizumab)

38
Q

resilizumab administration

A

iv with boxed warning for anaphylaxis

39
Q

benralizumab

A

sc every 8 weeks

40
Q

dupolumab

A

sc (il4/il3)

41
Q

order of inhalers

A

SABA1st, then LABA or LAMA, then ICS (60 seconds in between)

42
Q

red zone percent

A

less than 50% of personal best

43
Q

how to administer MDI

A

shake for 5 seconds before each spray, prime, breathe in slowly and deeply and hold for 10 seconds. Clean mouthpiece with rinsing once weekly. (for dulera and symbacort just wipe)

44
Q

Respiclick administration

A

Do not shake. No button. opening cap loads dose, do not open and close, breathe in deeply (a dpi) and hold for 10 seconds

45
Q

pulmacort flexhaler administration

A

Twisting loads dose. a dpi so breathe in deeply and forcefully and no need to prime. An ICS so rinse with water.

46
Q

advair discus counseling

A

hold like a hamburger. lever loads dose. a dpi so breathe in quickly and deeply. rinse and spit because ics.

47
Q

how long should ampules be used after opening

A

2 weeks

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