arrhythmias Flashcards
nexterone
amiodarone (1/2)
pacerone
amiodarone (2/2)
half life of amiodarone
40-60 days
amiodarone contraindications
iodine hypersensitivity
amiodarone monitoring
pulmonary toxicity, hepatotoxicity
amiodarone structure
contains two iodine molecules which explains ddi with thyroid meds and iodine sensitivity warning
warnings of amiodstone
optic neuropathy, photosensitivity, neuropathy
diltiazem contraindications
heart failure
what class causes gingival hyperplasia
ccbs
therapeutic range for digoxin
afib: 0.8 to 2
hf: 0.5 to 0.9
digoxin antidote
digifab
signs of dig tox
blurred vision, green yellow halos
digoxin dose adjust
if crcl<50 or if switching from oral to iv lower dose by 20-25%
disopyramide side effects
anticholinergic
quinine administration
take with food
which antiarrhythmics can cause dile
procainimide, quinine (coombs)
mostly class 1a
procainimide dosing
4-10 mcg/ml
leaching issues with pvc pneumonic
Leach - lorazepam Absorbs - Amiodarone To - Tacrolimus Take - Taxares In - Insulin Nutrients - Nitroglycerin
what form does lidocaine come in and what is that used for?
refractory vt/cardiac arrest
what kind of beta blocker is sotalol
non selective
when do you reduce frequency of sotalol dose?
when crcl<60
what form does ibulitide come in
iv
which antiarrhythmic needs continous monitoring?
dofetilide - continous ecg and crcl for a min of 3 days
what is the half life of adenosine
10 seconds
what is adenosine used in?
paroxysmal supraventricular tachycardia
flecainide is contraindicated in what
heart failure, MI
pneumonic for antiarrhythmic classification
1a) double quarter pounder
1b) lettuce, mayo,
1c) fries please.
2) because
3) dieting during stress is always
4) very difficult.
key drugs that prolong qt intervals
- class i (esp 1a) and iii antiarrhythmics
- antibiotics - quinolones and macrolides
- antidepressants - TCAs, SSRI, SNRI
- antimetic drugs - 5-HT3 receptor antagonists, dropinerol/phenothiazines
- most antipsyxhotics
- other: tacrolimus, donepezil, fingolimod, methadone
paroxysmal afib
terminates spontaneously or with intervention within 7 days of onset
persistent
lasts longer than 7 days
long standing persistent
lasts longer than 12 months
permenant afib
treatment choicd to stop trying to restore nsr
valvular
requires warfarin anticoagulation, afib with moderate to severe mitral stenosis
goal hr for symptomatic afib
less than 80
path of conduction
SA –> AV –> bundle of HIS –> purkinje fibers
what happens in phase 0
rapid ventricular depoloarizaion due to na influx
class 1 works here
what happens in phase 2 of ap
ca in, k out
what happens in phase 3 of ap
k out
class 3 works here