Thiamine

Question 1

Brand name of Thiamine

Answer 1

Betaxin

Question 2

Drug class of Thiamine

Answer 2

Vitamin B

Question 3

Indications for Thiamine

Answer 3

Coma of unknown origin (given with Dextrose), delirium tremens, beriberi, Wernicke encephalopathy

Question 4

Mechanism of action of Thiamine

Answer 4

Combines with ATP to form thiamine pyrophosphate coenzyme, which is a necessary component for carbohydrate metabolism. The brain is extremely sensitive to thiamine deficiency.

Question 5

Contraindications of Thiamine

Answer 5

None.

Question 6

Adverse Effects of Thiamine

Answer 6

Anxiety, dyspnea, respiratory failure, vasodilation, hypotension, nausea and vomiting

Question 7

Precautions of Thiamine

Answer 7

Dilute prior to delivery (pain at IV site)

Should always be given with glucose

Question 8

Adult dose and administration of Thiamine

Answer 8

100 mg slow IV or IM

Question 9

Pediatric dose and admin of Thiamine

Answer 9

10-25 mg slow IV or IM