Insulin

Question 1

What are brand names for insulin?

Answer 1

Humalog, Humulin, Novalog, Novolin, Lantus

Question 2

Drug class of insulin?

Answer 2

Hormone, anti-diabetic

Question 3

Indication for insulin?

Answer 3

Not use in emergency pre-hospital setting. Diabetic ketoacidosis or other hyperglycemic state, nonketotic hyperosmolar coma, hyperkalemia (insulin and D50 used together to lower hyperkalemic state).

Question 4

Mechanism of action of insulin?

Answer 4

Allows for glucose transport into the cells,
Glycogenesis and conversion of glycogen to
Fat. Produces an intracellular shift of K+,
Mg+ and Ca+

Question 5

Contraindications of insulin?

Answer 5

Hypoglycemia, hypokalemia

Question 6

Adverse effects of insulin

Answer 6

Weakness, fatigue, confusion, headache, seizure, coma, tachycardia, nausea, hypokalemia, hypoglycemic effects of insulin. Alcohol and salicylates may potentate the effects of insulin.

Question 7

Precautions of insulin

Answer 7

Incompatible in solution with any other drugs
ETOH and salicylates may potentiate
Effects of insulin

Question 8

Adult dose and admin of insulin

Answer 8

10-25 units SC/IM followed by infusion of 0.1 units/kg/h

Question 9

Pediatric dose of insulin

Answer 9

0.1-0.2 units/kg/h SC/IM/IV